Description

Filipin Complex is a polyene macrolide antibiotic complex derived from *Streptomyces filipinensis*, primarily recognized for its potent binding to membrane sterols, particularly cholesterol. This interaction makes it an invaluable tool for disrupting membrane integrity and studying lipid raft dynamics in biological research. It is essential for researchers and manufacturers in the pharmaceutical and life science sectors requiring a high-purity biochemical for antifungal studies, membrane biology, and diagnostic applications.

Application

• Biochemical Research: A critical tool for studying cholesterol distribution, membrane fluidity, and lipid raft organization in cell membranes.
• Antifungal Studies: Used as a reference standard and active agent in research investigating polyene antibiotics and their mechanisms of action against fungal pathogens.
• Diagnostic Reagent: Employed in laboratory assays and staining protocols to detect and visualize free cholesterol in tissues and biological samples.
• Pharmaceutical Intermediates: Serves as a starting material or reference compound in the development and quality control of antifungal pharmaceuticals.
• Cell Biology: Utilized to permeabilize cellular membranes in controlled experiments and to study the role of sterols in cell signaling and structure.

Basic Information

Product Name	Filipin Complex
CAS No.	11078-21-0
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Filipin; Filipin III Complex; Antibiotic A 246; U-5956; NSC 166071; NSC-166071; Filipin complex from Streptomyces filipinensis; Polyene antibiotic Filipin
EINECS	Contact for details

Quality Control

Our Filipin Complex is produced and tested under strict quality management protocols to ensure high purity and batch-to-batch consistency suitable for research and development. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and potency. We adhere to relevant industry standards, and specifications can be tailored to meet specific project requirements upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C under an inert atmosphere to minimize oxidation. The product is light-sensitive and easily oxidized; prolonged exposure to air, light, or elevated temperatures should be avoided to maintain stability and potency.

Specification

Item	Specification
Appearance	Yellow to brown powder
Identification (HPLC/IR)	Conforms to standard
Assay (HPLC)	≥ 95% (Filipin Complex)
Loss on Drying	≤ 5.0 %
Solubility	Soluble in DMSO, DMF; slightly soluble in methanol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.