Description

Penicilloic Acid CAS NO 11039-68-2 is a key intermediate and degradation product derived from penicillin antibiotics. Its significance lies in its role as a reference standard and a crucial building block for pharmaceutical research and development. This compound is primarily needed by manufacturers and research institutions in the pharmaceutical and biotechnology sectors for analytical method development, impurity profiling, and the synthesis of novel β-lactam derivatives.

Application

• Pharmaceutical Reference Standard: Used for the identification, assay, and impurity testing of penicillin-based drugs in quality control laboratories.
• Impurity Profiling: Serves as a critical marker for monitoring the degradation and stability of penicillin antibiotics during manufacturing and storage.
• Biochemical Research: Employed in studies investigating penicillin allergy mechanisms, as penicilloic acid is a major haptenic determinant.
• API Synthesis Intermediate: Acts as a precursor in the research and development of new semi-synthetic penicillin derivatives and related compounds.
• Analytical Method Development: Essential for developing and validating HPLC, LC-MS, and other chromatographic methods for antibiotic analysis.
• Educational & Forensic Analysis: Used in academic settings for teaching analytical chemistry and in forensic labs for drug analysis protocols.

Basic Information

Product Name	Penicilloic Acid
CAS No.	11039-68-2
Molecular Formula	C16H18N2O5S
Molecular Weight	350.39 g/mol
Synonyms	Benzylpenicilloic Acid; (2S,5R,6R)-6-(2-Phenylacetamido)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic Acid; 6-Aminopenicillanic Acid Derivative; Penicillin G Acid; Penicillanic Acid, 6-(phenylacetamido)-; Degradation Product of Penicillin G
EINECS	Contact for details

Quality Control

Our Penicilloic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets high-purity standards suitable for pharmaceutical research. Certificates of Analysis (COA) with detailed chromatographic data are provided for traceability and regulatory compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its sensitivity, the product should be handled under an inert atmosphere when appropriate and protected from excessive moisture to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.