Description

Colicin E1 is a highly specific bactericidal protein produced by certain strains of *Escherichia coli*, targeting and disrupting the vital functions of competing bacterial cells. Its precise mechanism of action makes it a valuable tool for fundamental microbiological research and a promising candidate for novel antibacterial strategies. This product is essential for researchers in microbiology, molecular biology, and biotechnology, particularly for studies involving bacterial competition, plasmid biology, and the development of targeted antimicrobial agents. Colicin E1 CAS NO 11032-88-5 is supplied as a high-purity, research-grade material.

Application

• Microbiological Research: Used as a model bacteriocin to study mechanisms of bacterial competition, colicinogeny, and plasmid dynamics.
• Molecular Biology Studies: Employed in research on protein import, pore-formation in membranes, and the structure-function relationships of bactericidal proteins.
• Antimicrobial Mechanism Investigation: Serves as a reference compound for exploring novel pathways to disrupt bacterial cell membranes and energy metabolism.
• Biotechnology Tool Development: Potential use in the design of engineered antimicrobial peptides or in food safety applications targeting specific pathogens.
• Educational & Diagnostic Applications: Used in academic laboratory settings and for developing specific bacterial identification or typing assays.

Basic Information

Product Name	Colicin E1
CAS No.	11032-88-5
Molecular Formula	Contact for details
Molecular Weight	~57 kDa (Monomer)
Synonyms	Colicin E1; Bacteriocin E1; ColE1 Protein; Colicin Type E1; E1 Colicin; Colicinogenic Factor E1; Protein Colicin E1
EINECS	Contact for details

Quality Control

Our Colicin E1 is produced and handled under controlled conditions to ensure high biological activity and purity for research applications. Each batch is subjected to rigorous quality testing, which may include SDS-PAGE for purity assessment and activity assays to confirm specific bactericidal potency. A comprehensive Certificate of Analysis (COA) detailing batch-specific results is available upon request to support your research and compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature before opening to minimize moisture condensation. For extended storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (SDS-PAGE)	Corresponds to standard
Purity (SDS-PAGE)	≥ 90%
Biological Activity (Assay)	Confirmed
Protein Content (UV)	Contact for details
Endotoxin (LAL)	< 1.0 EU/μg
Solubility	Soluble in appropriate aqueous buffers

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.