Description

Concanavalin A is a carbohydrate-binding protein (lectin) derived from the jack bean (*Canavalia ensiformis*). This high-purity biochemical reagent is essential for its specific affinity for α-D-mannosyl and α-D-glucosyl residues, making it a critical tool for glycobiology research and bioprocessing. It is primarily utilized by researchers and manufacturers in the life sciences, pharmaceutical, and diagnostic industries for applications such as cell separation, glycoprotein purification, and immunology studies. Our product, Concanavalin A CAS NO 11028-71-0, is supplied with guaranteed consistency and performance for demanding laboratory and process environments.

Application

• Glycoprotein and Glycopeptide Purification: Used in affinity chromatography columns to isolate and study glycoproteins.
• Cell Biology Research: Induces mitogenic stimulation of T-lymphocytes and is used to study cell agglutination and membrane dynamics.
• Immunology and Diagnostics: Serves as a reagent in lectin-based assays and biosensors for detecting specific carbohydrate structures.
• Histochemistry: Employed as a staining tool to localize glycoconjugates in tissue sections.
• Vaccine and Therapeutic Development: Used in the research and downstream processing of glycosylated biopharmaceuticals.
• Plant Biology Studies: Investigates plant lectin interactions and carbohydrate-mediated signaling pathways.

Basic Information

Product Name	Concanavalin A
CAS No.	11028-71-0
Molecular Formula	N/A (Protein)
Molecular Weight	~102-104 kDa (Tetramer)
Synonyms	Con A; Jack Bean Lectin; Canavalia ensiformis Lectin; Concanavalin; Concanavalin A Type IV; Concanavalin A from Canavalia ensiformis; α-D-mannosyl-binding lectin; α-D-glucosyl-binding lectin
EINECS	234-253-2

Quality Control

Our Concanavalin A is produced and tested under stringent quality management systems. Each lot is characterized for critical parameters including hemagglutination activity, carbohydrate specificity, and purity profile to ensure batch-to-batch consistency for research and industrial use. Certificates of Analysis (COA) detailing specifications such as activity (units/mg), protein content, and endotoxin levels are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C. The product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent moisture absorption, which can affect stability and activity. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (IR)	Conforms to standard
Protein Content (Biuret)	≥ 95%
Hemagglutination Activity	≥ 50 units/mg protein
Specificity	Agglutinates erythrocytes, inhibited by α-methyl-D-mannoside
Solubility	Soluble in water and buffers
pH (1% solution)	6.0 - 7.5
Endotoxin (LAL)	< 10 EU/mg

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.