Description

Properdin CAS NO 11016-39-0 is a key regulatory protein of the alternative complement pathway, playing a critical role in innate immunity. Its primary function is to stabilize the C3 convertase complex, thereby amplifying the complement response against pathogens. This makes it an essential reagent for researchers and developers in the fields of immunology, diagnostics, and biopharmaceuticals, particularly for studying complement-mediated diseases and developing therapeutic interventions.

Application

• Immunological Research: Fundamental studies on the activation, regulation, and biological functions of the alternative complement pathway.
• Diagnostic Development: Used as a critical component or standard in immunoassays and diagnostic kits for detecting complement activity or deficiencies.
• Drug Discovery & Biopharmaceuticals: Target validation and screening for novel therapeutics aimed at modulating the complement system in autoimmune, inflammatory, or infectious diseases.
• Quality Control & Standardization: Serves as a reference standard for the quality control of related biological products and reagents.
• Clinical Studies: Investigation of properdin levels and their correlation with disease states in various clinical research settings.

Basic Information

Product Name	Properdin
CAS No.	11016-39-0
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Complement Factor P; Factor P; P Factor; Properdin Factor P; C3 Proactivator; C3PA; Complement Component Properdin; Glycine-Rich β-Glycoprotein; GBG
EINECS	Contact for details

Quality Control

Our Properdin is produced and handled under stringent quality management protocols to ensure batch-to-batch consistency and biological activity. Each lot undergoes comprehensive analytical testing, including purity assessment and functional activity assays. A Certificate of Analysis (COA) detailing specific test results is provided with every shipment to support your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. This product is hygroscopic (moisture-sensitive); allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and moisture uptake. For extended storage, consider aliquoting to avoid repeated freeze-thaw cycles.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder or solid
Identification (SDS-PAGE / Immunoassay)	Conforms
Purity (SDS-PAGE)	≥ 90%
Biological Activity (Functional Assay)	Conforms to reference standard
Endotoxin Level (LAL)	< 1.0 EU/μg
Solubility	Soluble in appropriate aqueous buffers

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.