Description

Acetamide, 2,2,2-Trifluoro-n-(2-Hydroxyphenyl)- is a specialized fluorinated acetamide derivative that serves as a valuable synthetic intermediate. This compound is significant for its unique molecular structure, which combines a trifluoroacetamide group with a phenolic hydroxyl moiety, enabling its use in advanced chemical synthesis. It is primarily required by research and development laboratories and industrial manufacturers in the pharmaceutical and agrochemical sectors for creating novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly those requiring fluorinated aromatic systems for enhanced metabolic stability and bioavailability.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and pesticides where the trifluoromethyl group can improve biological activity and environmental persistence.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in coordination chemistry and catalysis, leveraging the phenolic oxygen and amide functionality.
• Material Science: Potential monomer or additive in the synthesis of advanced polymers with specific thermal or chemical resistance properties.
• Organic Synthesis Reagent: Employed in academic and industrial R&D for constructing complex heterocyclic compounds and conducting fluorination-related chemical transformations.

Basic Information

Product Name	Acetamide, 2,2,2-Trifluoro-n-(2-Hydroxyphenyl)-
CAS No.	10595-66-1
Molecular Formula	C8H6F3NO2
Molecular Weight	205.14 g/mol
Synonyms	N-(2-Hydroxyphenyl)-2,2,2-trifluoroacetamide; 2,2,2-Trifluoro-N-(2-hydroxyphenyl)acetamide; 2',2',2'-Trifluoroacet-o-anisidide; o-Hydroxytrifluoroacetanilide; 2-(Trifluoroacetamido)phenol; Trifluoroacetylamino-2-phenol; 2-Aminophenol trifluoroacetamide derivative; CAS 10595-66-1
EINECS	Contact for details

Quality Control

Our Acetamide, 2,2,2-Trifluoro-n-(2-Hydroxyphenyl)- is produced under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting key parameters such as assay, impurity profile, and physical characteristics are available for every shipment. We adhere to relevant industry standards and can support development projects requiring specific analytical methodologies or custom purity grades.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from strong acids, strong bases, and oxidizing agents. Due to the potential for light sensitivity, containers should be kept in opaque or amber packaging.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.