Description

Angiotensin I, Asn(1)-Val(5)-His(9)- is a specific, modified peptide fragment of the renin-angiotensin system (RAS) hormone Angiotensin I. This high-purity reference standard is critical for biochemical research, enabling precise study of enzyme kinetics, receptor interactions, and metabolic pathways. It is primarily utilized by pharmaceutical R&D teams, academic research institutions, and diagnostic kit manufacturers focused on cardiovascular and renal system biology.

Application

• Biochemical Research Standard: Used as a high-purity reference compound for studying the renin-angiotensin system (RAS) in vitro.
• Enzyme Substrate: Acts as a specific substrate for Angiotensin-Converting Enzyme (ACE) activity and inhibition assays.
• Pharmaceutical Development: Serves as a key intermediate or reference material in the research and development of cardiovascular therapeutics.
• Diagnostic Reagent Manufacturing: Employed in the production of calibration standards and controls for clinical diagnostic assays related to blood pressure regulation.
• Metabolic Pathway Analysis: Facilitates research into the proteolytic processing and metabolic fate of angiotensin peptides.
• Receptor Binding Studies: Used in competitive binding assays to characterize angiotensin receptor subtypes and screen for potential receptor antagonists.

Basic Information

Product Name	Angiotensin I, Asn(1)-Val(5)-His(9)-
CAS No.	10587-93-6
Molecular Formula	C62H89N17O14
Molecular Weight	1288.5 g/mol
Synonyms	Angiotensin I (5-L-Isoleucine); [Asn1, Val5, His9]-Angiotensin I; Asp-Arg-Val-Tyr-Ile-His-Pro-Phe-His-Leu; H-Asp-Arg-Val-Tyr-Ile-His-Pro-Phe-His-Leu-OH; DRVYIHPFHL; Ang I (1-10); Angiotensin I Human; Angiotensin I (human)
EINECS	Contact for details

Quality Control

Our Angiotensin I, Asn(1)-Val(5)-His(9)- is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity verification and mass spectrometry for identity confirmation, to ensure it meets the stringent requirements for research and development applications. Certificates of Analysis (COA) detailing all specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive) and should be allowed to equilibrate to room temperature in a desiccator before opening to prevent condensation and hydrolysis. For long-term storage, keep desiccated at -20°C.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80.0%
Solubility	Soluble in water, acetic acid, DMSO

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.