Description

α-Oxo-n-[(R)-1-Phenylethyl]Phenylacetamide is a high-purity chiral intermediate featuring a specific stereochemical configuration. This compound is valued for its role in the synthesis of enantiomerically pure pharmaceuticals and fine chemicals, where precise molecular architecture is critical for biological activity and process efficiency. It is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and advanced material sectors for developing active pharmaceutical ingredients (APIs) and specialty catalysts.

Application

• Pharmaceutical Intermediate: A key chiral building block in the synthesis of enantiomerically pure active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and cardiovascular drugs.
• Asymmetric Synthesis Catalyst Precursor: Used in the development and preparation of chiral ligands and organocatalysts for stereoselective chemical transformations.
• Agrochemical Research: Serves as an intermediate in the research and development of chiral pesticides and herbicides to enhance efficacy and reduce environmental impact.
• Fine Chemical Synthesis: Employed in academic and industrial R&D for constructing complex organic molecules with defined stereocenters.
• Reference Standard: Utilized as an analytical standard in quality control laboratories for method development and impurity profiling in chiral separations.

Basic Information

Product Name	α-Oxo-n-[(R)-1-Phenylethyl]Phenylacetamide
CAS No.	10549-15-2
Molecular Formula	C₁₆H₁₅NO₂
Molecular Weight	253.30 g/mol
Synonyms	(R)-N-(1-Phenylethyl)-2-oxo-2-phenylacetamide; (R)-α-Oxo-N-(1-phenylethyl)benzeneacetamide; N-[(1R)-1-Phenylethyl]-2-oxo-2-phenylacetamide; 2-Oxo-N-[(1R)-1-phenylethyl]-2-phenylacetamide; (R)-N-Phenethyl-2-oxo-2-phenylacetamide; (R)-α-Keto-N-(1-phenylethyl)phenylacetamide; (R)-Mandelic acid (1-phenylethyl)amide ketone
EINECS	Contact for details

Quality Control

Our α-Oxo-n-[(R)-1-Phenylethyl]Phenylacetamide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity assessment by HPLC, to ensure it meets the high standards required for synthetic applications. A Certificate of Analysis (COA) detailing identity, purity, and chiral excess is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee (R)
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.