Description

Z-D-Val-Onp CAS NO 10512-94-4 is a specialized N-protected amino acid derivative, specifically the p-nitrophenyl ester of Z-D-valine, designed for use in sophisticated peptide synthesis. This compound is a critical building block for the controlled, racemization-free formation of peptide bonds, ensuring the high stereochemical purity of the final product. It is essential for research and development laboratories in the pharmaceutical and biotechnology sectors, particularly those focused on developing novel therapeutic peptides, peptidomimetics, and complex organic molecules.

Application

• Solid-Phase Peptide Synthesis (SPPS): As an activated ester for the efficient, high-yield incorporation of D-valine residues into peptide chains.
• Solution-Phase Peptide Synthesis: Used in classical coupling strategies for the synthesis of short peptides and peptide fragments.
• Pharmaceutical Intermediate: A key precursor in the research and production of active pharmaceutical ingredients (APIs) with valine motifs.
• Bioconjugation: Employed for the site-specific labeling or modification of proteins, antibodies, and other biomolecules.
• Combinatorial Chemistry: A valuable reagent in libraries for drug discovery, enabling the rapid assembly of diverse compound arrays.
• Academic & Industrial R&D: Fundamental research tool in medicinal chemistry, chemical biology, and material science for creating novel structures.

Basic Information

Product Name	Z-D-Val-Onp
CAS No.	10512-94-4
Molecular Formula	C19H20N2O6
Molecular Weight	372.38 g/mol
Synonyms	N-Carbobenzoxy-D-valine p-nitrophenyl ester; Z-D-Val-ONp; Cbz-D-Val-ONp; Benzyloxycarbonyl-D-valine 4-nitrophenyl ester; (R)-2-(((Benzyloxy)carbonyl)amino)-3-methylbutanoic acid 4-nitrophenyl ester; D-Valine, N-[(phenylmethoxy)carbonyl]-, 4-nitrophenyl ester; N-(Benzyloxycarbonyl)-D-valine p-nitrophenyl ester
EINECS	Contact for details

Quality Control

Our Z-D-Val-Onp is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral analysis to confirm stereochemical integrity, ensuring compliance with research-grade standards. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee reproducible performance in your synthetic applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C (refrigerated) or as indicated on the label or COA. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and reactivity. Allow the container to reach room temperature in a dry environment before opening.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% D-isomer
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.