Description

Dnp-γ-Amino-n-Butyric Acid is a chemically modified derivative of the essential neurotransmitter γ-aminobutyric acid (GABA), featuring a dinitrophenyl (Dnp) protecting group. This compound is a critical intermediate and research tool in organic synthesis and neurochemistry, valued for its role in peptide synthesis and biochemical studies. It is primarily utilized by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers developing novel bioactive molecules and diagnostic reagents.

Application

• Pharmaceutical Research & Development: Serves as a key protected intermediate in the solid-phase and solution-phase synthesis of GABA-analog peptides and neuroactive compounds.
• Biochemical Labeling & Probes: Used in the preparation of labeled derivatives and affinity probes for studying GABA receptors and transport mechanisms.
• Organic Synthesis Building Block: Acts as a versatile synthon for introducing the GABA moiety into more complex molecular architectures with the amine functionality protected.
• Analytical Reference Standard: Employed as a high-purity standard in chromatographic methods (HPLC, LC-MS) for quality control and metabolic studies.
• Neuroscience Research: Utilized in experimental protocols to investigate the metabolism and function of GABAergic systems.

Basic Information

Product Name	Dnp-γ-Amino-n-Butyric Acid
CAS No.	10466-75-8
Molecular Formula	C11H13N3O6
Molecular Weight	283.24 g/mol
Synonyms	N-(2,4-Dinitrophenyl)-γ-aminobutyric acid; DNP-γ-Abu-OH; DNP-GABA; 4-[(2,4-Dinitrophenyl)amino]butanoic acid; γ-Aminobutyric acid N-2,4-dinitrophenyl derivative; GABA Dnp derivative; N-γ-Aminobutyryl-2,4-dinitroaniline
EINECS	Contact for details

Quality Control

Our Dnp-γ-Amino-n-Butyric Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, IR and NMR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.