Description

H-Dl-Leu-Nh2 Hcl is a high-purity, non-natural amino acid derivative widely used in pharmaceutical research and peptide synthesis. This compound serves as a critical chiral building block and intermediate for developing novel therapeutic agents and biochemical tools. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors who require reliable, high-quality raw materials for advanced synthesis.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs) and peptide-based drugs.
• Peptide Synthesis: Used as a protected leucine derivative in solid-phase and solution-phase peptide synthesis to construct complex peptide sequences.
• Biochemical Research: Employed in studies of enzyme mechanisms, protein structure-function relationships, and as a substrate or inhibitor analog.
• Fine Chemical Production: Acts as a versatile building block for the synthesis of specialized chemicals, including chiral ligands and catalysts.
• Reference Standard: Serves as an analytical standard in quality control laboratories for method development and validation in pharmaceutical analysis.

Basic Information

Product Name	H-Dl-Leu-Nh2 Hcl
CAS No.	10466-60-1
Molecular Formula	C6H15ClN2O
Molecular Weight	166.65 g/mol
Synonyms	DL-Leucinamide hydrochloride; (±)-2-Amino-4-methylpentanamide hydrochloride; H-DL-Leu-NH2·HCl; Leucinamide, DL-, hydrochloride; 2-Amino-4-methylvaleramide hydrochloride; (RS)-2-Amino-4-methylpentanamide hydrochloride; DL-2-Amino-4-methylvaleramide hydrochloride; DL-Leu-NH2·HCl
EINECS	233-951-1

Quality Control

Our H-Dl-Leu-Nh2 Hcl is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation, to ensure it meets the high standards required for research and pharmaceutical applications. Certificates of Analysis (COA) with detailed specifications are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Optical Rotation	± 0.5° (c=1 in H2O)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.