Description

H-Ile-Nh2 Hcl is a high-purity, protected amino acid derivative, specifically the hydrochloride salt of L-Isoleucine amide. This compound serves as a critical building block in the synthesis of complex peptides and active pharmaceutical ingredients (APIs), offering precise stereochemical control. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors who require reliable, high-quality intermediates for advanced organic synthesis.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of peptide-based drugs and therapeutic agents.
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis (SPPS) as a protected amino acid component.
• Biochemical Research: Employed in proteomics research and as a standard or reagent in enzymatic studies.
• API Development: Integral to the research and development of new active pharmaceutical ingredients requiring the L-Isoleucine moiety.
• Fine Chemical Production: Serves as a precursor in the manufacture of specialized catalysts and complex organic molecules.

Basic Information

Item	Details
Product Name	H-Ile-Nh2 Hcl
CAS No.	10466-56-5
Molecular Formula	C6H15ClN2O
Molecular Weight	166.65 g/mol
Synonyms	L-Isoleucine amide hydrochloride; H-Ile-NH2·HCl; Isoleucinamide hydrochloride; (2S,3S)-2-Amino-3-methylpentanamide hydrochloride; Ile-NH2·HCl; Fmoc-Ile-NH2·HCl (precursor form); (S,S)-Isoleucine amide HCl; 2-Amino-3-methylvaleramide hydrochloride
EINECS	Contact for details

Quality Control

Our H-Ile-Nh2 Hcl is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation to ensure it meets exacting standards for pharmaceutical and research applications. Certificates of Analysis (COA) detailing all specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% (L-isomer)
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.