Description

α-Msh CAS NO 10466-28-1 is a synthetic peptide analog of the endogenous α-melanocyte-stimulating hormone (α-MSH). This compound is of significant interest in biochemical and pharmaceutical research due to its role in modulating melanogenesis and its potential anti-inflammatory and immunomodulatory effects. It is primarily utilized by research institutions and pharmaceutical developers focused on dermatology, pigmentary disorders, and novel therapeutic pathways.

Application

• Biomedical Research: Used as a reference standard and active agent in studies investigating melanocortin receptor (MCR) signaling pathways.
• Dermatology & Cosmeceuticals: Exploration of applications in skin pigmentation disorders, tanning response, and potential inclusion in advanced skincare formulations.
• Pharmacology Development: Serves as a key intermediate or lead compound in the development of novel therapeutics for inflammation, appetite regulation, and sexual function.
• In Vitro Diagnostics: Employed in assay development and calibration for detecting and quantifying melanocortin system components.
• Academic Studies: Fundamental research tool in universities and labs studying neuroendocrinology, peptide biology, and receptor-ligand interactions.

Basic Information

Item	Detail
Product Name	α-Msh
CAS No.	10466-28-1
Molecular Formula	C77H109N21O19S
Molecular Weight	1664.9 g/mol
Synonyms	α-MSH; α-Melanocyte Stimulating Hormone; α-Melanotropin; Ac-Ser-Tyr-Ser-Met-Glu-His-Phe-Arg-Trp-Gly-Lys-Pro-Val-NH2; Melanotropin (alpha); N-Acetyl-α-melanocyte-stimulating hormone; Intermedin (former name); 13-Amino acid peptide α-MSH
EINECS	Contact for details

Quality Control

Our α-Msh is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and mass spectrometry for identity confirmation, to ensure it meets high-grade research specifications. A Certificate of Analysis (COA) detailing purity, peptide content, and solvent residues is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. The product is hygroscopic (moisture-sensitive). For long-term storage, consider desiccant and under an inert atmosphere. Allow the vial to reach room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC & MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80% (by weight)
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10.0%
Single Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.