Description

Bromperidol CAS NO 10457-90-6 is a potent butyrophenone derivative belonging to the class of typical antipsychotic agents. Its primary value lies in its high-affinity antagonism of dopamine D2 receptors, making it a critical compound for neurological and psychiatric research. This active pharmaceutical ingredient (API) is essential for researchers and developers in the pharmaceutical industry focusing on central nervous system (CNS) disorders, antipsychotic drug development, and neuropharmacology studies.

Application

• Pharmaceutical Reference Standard: Used as a certified reference material (CRM) for quality control and analytical method development in drug manufacturing.
• Neuropharmacology Research: A key tool for studying dopamine receptor function, antipsychotic mechanisms of action, and the pathophysiology of schizophrenia.
• Active Pharmaceutical Ingredient (API): Serves as the core therapeutic agent in the formulation development of antipsychotic medications.
• Biochemical Assay Development: Employed in competitive binding assays and high-throughput screening (HTS) to identify novel CNS-active compounds.
• Metabolic and Pharmacokinetic Studies: Used to investigate the absorption, distribution, metabolism, and excretion (ADME) profiles of butyrophenone drugs.
• Academic and Clinical Research: Supports fundamental and translational research in universities, hospitals, and contract research organizations (CROs).

Basic Information

Product Name	Bromperidol
CAS No.	10457-90-6
Molecular Formula	C21H23BrFNO2
Molecular Weight	420.32 g/mol
Synonyms	4-[4-(4-Bromophenyl)-4-hydroxypiperidino]-4'-fluorobutyrophenone; Bromperidolum; Impromen; Azurene; 4'-Fluoro-4-[4-(p-bromophenyl)-4-hydroxypiperidino]butyrophenone; R-11333; Bromperidol Hydrochloride (salt form)
EINECS	233-950-4

Quality Control

Our Bromperidol is manufactured under strict quality management systems to ensure batch-to-batch consistency and reliability for research purposes. Each lot undergoes comprehensive analytical testing, including identification, purity assay, and impurity profiling using advanced techniques like HPLC and GC. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with our stringent in-house specifications.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature, typically between 15°C and 25°C (59°F and 77°F), in a dry, well-ventilated area. Keep the container tightly sealed to protect the hygroscopic material from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.