Description

Boc-Bpa-Oh CAS NO 10454-43-0 is a high-purity, protected amino acid derivative, specifically N-(tert-Butoxycarbonyl)-4-benzoyl-L-phenylalanine. This compound serves as a critical building block in the synthesis of complex peptides and peptidomimetics, offering precise control over molecular structure. It is essential for researchers and manufacturers in the pharmaceutical and biotechnology sectors who require reliable, high-quality intermediates for drug discovery and development processes.

Application

• Pharmaceutical Intermediate: A key precursor in the solid-phase and solution-phase synthesis of therapeutic peptides and peptide-based drug candidates.
• Protease Inhibitor Development: Used in the research and construction of protease inhibitor molecules due to its benzophenone moiety, which can facilitate photoaffinity labeling studies.
• Bioconjugation & Linker Chemistry: Employed in the design of peptide conjugates, linkers, and molecular probes for targeted drug delivery and diagnostic applications.
• Academic & Industrial R&D: Serves as a standard reagent in research laboratories for studying peptide structure-activity relationships (SAR) and developing novel bioactive compounds.
• Material Science: Potential use in the synthesis of specialized polymers and advanced materials where peptide-like sequences are incorporated for specific functional properties.

Basic Information

Product Name	Boc-Bpa-Oh
CAS No.	10454-43-0
Molecular Formula	C₂₁H₂₃NO₅
Molecular Weight	369.41 g/mol
Synonyms	N-(tert-Butoxycarbonyl)-4-benzoyl-L-phenylalanine; Boc-4-Benzoyl-L-phenylalanine; Boc-Bpa-OH; (2S)-2-[(2-Methylpropan-2-yl)oxycarbonylamino]-3-[4-(phenylcarbonyl)phenyl]propanoic acid; N-Boc-4-benzoyl-L-phenylalanine; Nα-Boc-4-benzoyl-L-phenylalanine; Boc-L-Bpa-OH; tert-Butyloxycarbonyl-4-benzoyl-L-phenylalanine
EINECS	Contact for details

Quality Control

Our Boc-Bpa-Oh is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation (IR, NMR) to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) with detailed specifications are provided for every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed and desiccated when not in use to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Optical Rotation [α]²⁰D	Contact for details
Chiral Purity (HPLC)	≥99.0%
Water Content (KF)	≤0.5%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.