Description

n-(2,4-Dinitrophenyl)-L-Alanine Methyl Ester is a specialized chiral amino acid derivative featuring a dinitrophenyl protecting group. This compound is of significant value in organic synthesis and biochemical research, serving as a key intermediate for the preparation of modified peptides and as a reagent for studying enzyme mechanisms. It is primarily utilized by research institutions and pharmaceutical development laboratories engaged in advanced synthetic chemistry and proteomics.

Application

• Peptide Synthesis Intermediate: Used as a protected amino acid building block in solid-phase and solution-phase peptide synthesis.
• Biochemical Research: Acts as a substrate or inhibitor in enzymatic studies, particularly for proteases and transferases.
• Chromatographic Reference Standard: Employed as a standard in HPLC and LC-MS methods for method development and quality control.
• Organic Synthesis Reagent: Serves as a precursor for the synthesis of more complex chiral molecules and pharmaceutical candidates.
• Protecting Group Chemistry: The 2,4-dinitrophenyl (Dnp) group is used in selective protection and deprotection strategies.

Basic Information

Product Name	n-(2,4-Dinitrophenyl)-L-Alanine Methyl Ester
CAS No.	10420-63-0
Molecular Formula	C10H11N3O6
Molecular Weight	269.21 g/mol
Synonyms	L-Alanine, N-(2,4-dinitrophenyl)-, methyl ester; Methyl N-(2,4-dinitrophenyl)-L-alaninate; (S)-Methyl 2-((2,4-dinitrophenyl)amino)propanoate; DNP-L-Ala-OMe; Dnp-L-Alanine methyl ester; N-Dnp-L-alanine methyl ester; Methyl (S)-2-[(2,4-dinitrophenyl)amino]propanoate
EINECS	Contact for details

Quality Control

Our n-(2,4-Dinitrophenyl)-L-Alanine Methyl Ester is produced and tested under a strict quality management system. Each batch undergoes comprehensive analysis to ensure identity, purity, and consistency, meeting the high standards required for research and development applications. A Certificate of Analysis (COA) detailing specific results for purity, chiral purity, and related substances is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% (L-isomer)
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.