Description

5,5'-(Sebacoyldiimino)Bis[2,4,6-Triiodo-3-(Propylcarbamoyl)Benzoic Acid] is a high-purity, iodinated organic compound primarily used as a key intermediate in the synthesis of specialized X-ray contrast media. This compound matters because it provides the essential iodine-rich scaffold required for effective radiopacity in diagnostic imaging agents, directly impacting product efficacy and regulatory compliance. Pharmaceutical manufacturers and advanced chemical synthesis facilities need this material for developing next-generation non-ionic, low-osmolar contrast agents, where precise chemical structure and purity are critical for safety and performance.

Application

• Pharmaceutical Intermediate: Primary building block for the synthesis of non-ionic X-ray contrast media such as Iopromide, Ioversol, and Iopamidol analogs.
• Diagnostic Imaging Agent Precursor: Serves as the core iodinated structure in the development of advanced intravascular and intrathecal contrast agents.
• Research & Development: Used in academic and industrial R&D for creating novel iodinated compounds with potential diagnostic or therapeutic applications.
• Custom Synthesis: Employed in contract manufacturing organizations (CMOs) for the production of bespoke contrast media under cGMP conditions.
• Radiopharmaceutical Chemistry: Potential use as a precursor or modifier in the development of targeted imaging agents.

Basic Information

Product Name	5,5'-(Sebacoyldiimino)Bis[2,4,6-Triiodo-3-(Propylcarbamoyl)Benzoic Acid]
CAS No.	10395-30-9
Molecular Formula	C34H32I6N4O8
Molecular Weight	1446.96 g/mol
Synonyms	Sebacoyldiimino Bis(2,4,6-Triiodo-3-(Propylcarbamoyl)Benzoic Acid); Iopromide Intermediate; Ioversol Intermediate; 5,5'-Sebacoyldiimino-bis(2,4,6-triiodo-N-propylisophthalamic acid); Bis(3-carboxy-2,4,6-triiodo-5-(propylcarbamoyl)phenyl) sebacamide; Non-Ionic Contrast Media Intermediate; Iodinated Benzoic Acid Derivative; CT Contrast Agent Precursor
EINECS	Contact for details

Quality Control

Our production of this critical pharmaceutical intermediate adheres to strict cGMP guidelines to ensure batch-to-batch consistency and traceability. Quality is verified through a comprehensive battery of tests including HPLC for purity and related substances, residual solvent analysis, and elemental analysis for iodine content. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications. We support audits and can supply documentation for regulatory filings (e.g., DMF, CEP).

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep the container tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single unknown impurity ≤ 0.5%
Iodine Content	52.0% - 53.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Heavy Metals	≤ 10 ppm
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.