Description

3-Iodopyridine-4-Carbonitrile is a versatile halogenated pyridine derivative that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring both an iodine substituent and a nitrile group, makes it a valuable precursor for constructing complex heterocyclic systems and functionalized molecules. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries, enabling the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Building block for creating novel herbicides, fungicides, and insecticides with enhanced efficacy.
• Ligand and Catalyst Development: Used to prepare sophisticated ligands for transition metal catalysis and organocatalysts.
• Material Science Research: Serves as a monomer or functionalization agent in the development of conductive polymers and organic electronic materials.
• Cross-Coupling Reactions: Ideal substrate for palladium-catalyzed reactions like Suzuki, Sonogashira, and Heck couplings due to the reactive iodine atom.
• Nucleic Acid Chemistry: Potential intermediate for modifying nucleosides or creating novel fluorescent probes and tags.

Basic Information

Product Name	3-Iodopyridine-4-Carbonitrile
CAS No.	10386-28-4
Molecular Formula	C6H3IN2
Molecular Weight	230.01 g/mol
Synonyms	4-Cyano-3-iodopyridine; 3-Iodo-4-cyanopyridine; 3-Iodopyridine-4-carbonitrile; 4-Pyridinecarbonitrile, 3-iodo-; 3-Iodoisonicotinonitrile; 3-Iodo-4-pyridinecarbonitrile; Pyridine, 4-cyano-3-iodo-
EINECS	Contact for details

Quality Control

Our 3-Iodopyridine-4-Carbonitrile is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to verify identity and purity. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We support compliance with REACH and other global regulatory frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.