Description

1-O,3-O,4-O,6-o-Tetraacetyl-2-(Acetylamino)-2-Deoxy-α-D-Galactopyranose is a key protected monosaccharide derivative, specifically a peracetylated N-acetylgalactosamine (GalNAc) building block. This compound is essential for synthetic chemists as it provides a versatile, reactive intermediate with hydroxyl groups masked as acetate esters, enabling selective deprotection strategies. It is primarily required by research institutions and pharmaceutical companies engaged in the synthesis of complex glycoconjugates, oligosaccharides, and biologically active molecules for drug discovery and development.

Application

• Glycochemistry & Carbohydrate Synthesis: A fundamental starting material for the controlled synthesis of oligosaccharides and glycoconjugates.
• Pharmaceutical Intermediates: Serves as a critical precursor in the production of glycosylated drugs, prodrugs, and diagnostic agents.
• Bioconjugation & Probe Development: Used to introduce GalNAc moieties onto proteins, peptides, or other biomolecules for targeted delivery or labeling studies.
• Glycosidase Inhibitor Research: Acts as a substrate analog or intermediate in the development of enzyme inhibitors.
• Material Science: Potential monomer for creating novel bio-based polymers or surface coatings with specific carbohydrate functionalities.
• Standards & Reference Materials: Supplied as a high-purity analytical standard for quality control and research validation in carbohydrate analysis.

Basic Information

Product Name	1-O,3-O,4-O,6-o-Tetraacetyl-2-(Acetylamino)-2-Deoxy-α-D-Galactopyranose
CAS No.	10385-50-9
Molecular Formula	C16H23NO10
Molecular Weight	389.35 g/mol
Synonyms	2-Acetamido-1,3,4,6-tetra-O-acetyl-2-deoxy-α-D-galactopyranose; α-D-GalNAc pentaacetate; N-Acetyl-α-D-galactosamine pentaacetate; Penta-O-acetyl-α-D-galactosamine; 1,3,4,6-Tetra-O-acetyl-2-acetamido-2-deoxy-α-D-galactopyranose; α-D-Galactosamine pentaacetate; Ac4GalNAcα; GalNAc(α1-)-OAc4
EINECS	Contact for details

Quality Control

Our 1-O,3-O,4-O,6-o-Tetraacetyl-2-(Acetylamino)-2-Deoxy-α-D-Galactopyranose is manufactured under strict quality protocols to ensure batch-to-batch consistency and high purity suitable for research and synthesis. We provide comprehensive analytical data including HPLC purity, optical rotation, and spectroscopic confirmation (NMR, IR). Certificates of Analysis (COA) detailing all specifications are available upon request for every lot, supporting compliance with internal quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation due to moisture absorption. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Specific Optical Rotation [α]²⁰D	+105° to +115° (c=1 in CHCl₃)
Melting Point	158°C - 165°C
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.