Description

n-o-Nitrophenylsulfenyl-L-Isoleucine*Dch A is a specialized, high-purity amino acid derivative primarily used as a key intermediate in advanced pharmaceutical synthesis and peptide research. This compound is critical for the development and production of complex peptide-based therapeutics, where precise molecular structure and purity are paramount. It is essential for research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers focused on innovative drug discovery and process development.

Application

• Pharmaceutical Intermediate: A crucial building block in the solid-phase and solution-phase synthesis of novel peptide drugs and bioactive peptides.
• Peptide Research: Used in academic and industrial research for studying peptide structure-activity relationships (SAR) and developing new synthetic methodologies.
• Protecting Group Chemistry: The nitrophenylsulfenyl (Nps) group serves as a temporary protecting group for amino acids during multi-step peptide synthesis, allowing for selective deprotection.
• API Development: Employed in the research and development stages of Active Pharmaceutical Ingredients (APIs) that incorporate modified isoleucine residues.
• Bioconjugation: Potential use in the creation of peptide-protein conjugates or labeled peptides for diagnostic and therapeutic applications.
• Reference Standard: Serves as a high-purity analytical standard for quality control in peptide manufacturing and related chemical processes.

Basic Information

Product Name	n-o-Nitrophenylsulfenyl-L-Isoleucine*Dch A
CAS No.	10382-52-2
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	NPS-Ile-OH; 2-Nitrophenylsulfenyl-L-isoleucine; L-Isoleucine, N-(2-nitrophenylthio)-; N-(o-Nitrophenylthio)-L-isoleucine; o-Nitrophenylsulfenyl-L-isoleucine; Nps-L-Ile-OH; 2-Nitrobenzenesulfenyl-L-isoleucine; N-(2-Nitrophenylsulfanyl)-L-isoleucine
EINECS	Contact for details

Quality Control

Our n-o-Nitrophenylsulfenyl-L-Isoleucine*Dch A is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and pharmaceutical applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using a desiccant.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Optical Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.