Description

n-Benzoylimidazole is a versatile and highly reactive chemical building block, primarily used as an acylating agent for the synthesis of amides and esters under mild conditions. Its significance lies in its ability to efficiently transfer the benzoyl group to nucleophiles, making it a valuable reagent in organic synthesis and pharmaceutical research. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries who require high-purity intermediates for complex molecule construction.

Application

• Pharmaceutical Intermediate: A key reagent in the synthesis of active pharmaceutical ingredients (APIs), particularly for constructing amide bonds in drug candidates.
• Peptide Synthesis: Used as a benzoylating agent in the protection of amino groups during solid-phase and solution-phase peptide synthesis.
• Agrochemical Manufacturing: Serves as an intermediate in the production of certain herbicides, fungicides, and plant growth regulators.
• Polymer Chemistry: Acts as a monomer or modifying agent in the synthesis of specialty polymers and functional materials.
• Bioconjugation: Employed in biochemical research for labeling proteins and other biomolecules with benzoyl groups.
• Catalyst and Ligand Synthesis: A precursor for creating N-heterocyclic carbene (NHC) ligands and other organocatalysts.
• Organic Synthesis Research: A fundamental tool in academic and industrial R&D labs for exploring new benzoylation methodologies.

Basic Information

Item	Detail
Product Name	n-Benzoylimidazole
CAS No.	10364-94-0
Molecular Formula	C10H8N2O
Molecular Weight	172.18 g/mol
Synonyms	1-Benzoylimidazole; N-Benzoylimidazole; Imidazole, 1-benzoyl-; Benzoic acid imidazolide; BZI; 1H-Imidazole, 1-benzoyl-; Benzoyl imidazole; NSC 403697
EINECS	233-819-6

Quality Control

Our n-Benzoylimidazole is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and spectroscopic identification (IR, NMR), to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) with detailed specifications are provided for every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids, strong bases, and oxidizing agents. The product is moisture-sensitive; ensure containers are sealed tightly after use to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	118 - 122 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.