Description

H-Arg(No2)-Obzl p-Tosylate is a protected arginine derivative, specifically the nitro-guanidino form with benzyl ester and p-toluenesulfonate salt functionalities. This compound is a critical building block in peptide synthesis, offering precise control over the introduction of the arginine residue while protecting its reactive side chain. It is essential for researchers and manufacturers in the pharmaceutical and biotechnology sectors who require high-purity intermediates for the development of novel therapeutic peptides and biochemical probes.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key protected intermediate for the controlled incorporation of arginine into peptide chains.
• Solution-Phase Peptide Synthesis: Used in classical coupling strategies for constructing complex peptide sequences.
• Pharmaceutical Research: Serves as a precursor in the development of peptide-based drugs targeting various diseases.
• Bioconjugation: Acts as a linker or modified amino acid for attaching peptides to other molecules, surfaces, or probes.
• Biochemical Tool Development: Used to create substrates, inhibitors, or labeled peptides for enzymatic studies and diagnostic assays.
• Academic Research: A valuable reagent for studying peptide structure, function, and interactions in university and institutional labs.

Basic Information

Product Name	H-Arg(No2)-Obzl p-Tosylate
CAS No.	10342-07-1
Molecular Formula	C21H28N6O7S
Molecular Weight	508.55 g/mol
Synonyms	NG-Nitro-L-arginine benzyl ester p-toluenesulfonate salt; H-Arg(NO2)-OBzl·TosOH; Benzyl NG-nitro-L-argininate 4-methylbenzenesulfonate; L-Arginine, N2-[(phenylmethoxy)carbonyl]-NG-nitro-, 4-methylbenzenesulfonate; Arg(NO2)-OBzl Tosylate; NO2-Arg-OBzl p-TsOH
EINECS	Contact for details

Quality Control

Our H-Arg(No2)-Obzl p-Tosylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and cGMP manufacturing. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Assay	≥ 97.0% (on anhydrous basis)
Specific Rotation	[α]D20: Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.