Description

Boc-Ser(Bzl)-Oh Dcha is a protected amino acid derivative, specifically the tert-butoxycarbonyl (Boc) and benzyl (Bzl) protected form of serine, supplied as a dicyclohexylamine (DCHA) salt. This compound is a critical building block in solid-phase peptide synthesis (SPPS), offering enhanced stability and solubility for complex peptide chain assembly. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of therapeutic peptides, peptide hormones, and biochemical probes.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key protected intermediate for the controlled, sequential addition of serine residues during automated or manual peptide synthesis.
• Therapeutic Peptide Development: Used in the research and production of peptide-based pharmaceuticals targeting metabolic disorders, oncology, and infectious diseases.
• Bioconjugation and Labeling: Serves as a precursor for introducing serine sites intended for further modification with fluorescent tags, PEG chains, or other functional groups.
• Chemical Biology Research: Employed in studying protein-protein interactions, enzyme mechanisms, and signal transduction pathways by incorporating modified serine analogs.
• Process Development & Scale-Up: Suitable for transitioning from laboratory-scale research to pilot and commercial-scale GMP manufacturing of peptide active pharmaceutical ingredients (APIs).

Basic Information

Product Name	Boc-Ser(Bzl)-Oh Dcha
CAS No.	10342-01-5
Molecular Formula	C21H33N3O5
Molecular Weight	407.50 g/mol
Synonyms	N-α-(tert-Butoxycarbonyl)-O-benzyl-L-serine dicyclohexylamine salt; Boc-O-benzyl-L-serine DCHA salt; Boc-Ser(Bzl)-OH·DCHA; (2S)-2-[(2-Methylpropan-2-yl)oxycarbonylamino]-3-(phenylmethoxy)propanoic acid - N-cyclohexylcyclohexanamine (1:1); tert-Butoxycarbonyl-O-benzyl-L-serine dicyclohexylammonium salt; Boc-L-Ser(Bzl)-OH DCHA salt; BOC-SER(BZL)-OH DCHA SALT
EINECS	Contact for details

Quality Control

Our Boc-Ser(Bzl)-Oh Dcha is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis for enantiomeric excess, and identity confirmation via IR and NMR spectroscopy. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to ensure traceability and compliance with your research or cGMP guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥98.5%
Optical Rotation	[α]²⁰D = Specific range provided on COA
Chiral Purity (HPLC)	≥99.0%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.