Description

6-Chloro-1-Hexyne is a versatile halogenated alkyne building block, essential for advanced organic synthesis. Its terminal alkyne and chloro functionalities make it a critical intermediate for constructing complex molecular architectures via cross-coupling and click chemistry reactions. This high-purity compound is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty materials sectors for developing active ingredients and novel polymers.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly for creating sp3-rich frameworks.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and plant growth regulators, leveraging its reactivity for structural diversification.
• Material Science & Polymer Chemistry: Acts as a monomer or cross-linking agent in the development of specialty polymers, coatings, and adhesives with tailored properties.
• Organic Synthesis & Research: A fundamental reagent for Sonogashira, Glaser, and other metal-catalyzed cross-coupling reactions in academic and industrial R&D laboratories.
• Liquid Crystal & OLED Material Precursor: Employed in the synthesis of organic electronic materials and liquid crystal compounds due to its rigid linear structure.
• Bioconjugation & Probe Development: Utilized in bioconjugation chemistry for labeling biomolecules, facilitated by its terminal alkyne group for copper-catalyzed azide-alkyne cycloaddition (CuAAC).

Basic Information

Item	Detail
Product Name	6-Chloro-1-Hexyne
CAS No.	10297-06-0
Molecular Formula	C6H9Cl
Molecular Weight	116.59 g/mol
Synonyms	1-Chloro-5-hexyne; 5-Hexyn-1-yl chloride; 6-Chlorohex-1-yne; Chlorohex-1-yne; 1-Hexyne, 6-chloro-; 6-Chloro-1-hexyne; 6-Chlorohex-1-yne; 5-Hexynyl chloride
EINECS	Contact for details

Quality Control

Our production of 6-Chloro-1-Hexyne adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistent performance. We provide traceable Certificates of Analysis (COA) with each shipment, confirming compliance with agreed specifications. Our quality system is designed to meet the rigorous demands of GMP and ISO standards for fine chemical manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated place at a controlled room temperature (15-25°C/59-77°F). Due to its highly volatile and light-sensitive nature, containers must be kept tightly sealed and away from heat, sparks, and open flame. Store separately from strong oxidizing agents.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Density (20°C)	0.95 - 0.98 g/mL
Refractive Index (n20D)	1.445 - 1.455

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.