Description

D-Proline, 1-Amino- (9Ci) is a non-proteinogenic amino acid derivative and a stereoisomer of the naturally occurring L-proline. This compound matters as a valuable chiral building block and intermediate in organic synthesis, particularly for the development of pharmaceuticals and bioactive molecules. It is needed by researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries for applications in asymmetric synthesis, peptide mimetics, and medicinal chemistry.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the asymmetric synthesis of active pharmaceutical ingredients (APIs) and drug candidates.
• Peptidomimetics Research: Used to construct modified peptide structures to enhance stability, bioavailability, and biological activity.
• Catalyst and Ligand Development: Serves as a precursor for chiral catalysts and ligands used in enantioselective transformations.
• Agrochemical Synthesis: An intermediate in the production of certain herbicides, fungicides, and plant growth regulators.
• Biochemical Research: Employed in studies of enzyme inhibition, metabolic pathways, and as a standard in analytical chemistry.
• Fine Chemical Production: Used in the manufacture of specialty chemicals, flavors, and fragrances requiring specific stereochemistry.

Basic Information

Item	Detail
Product Name	D-Proline, 1-Amino- (9Ci)
CAS No.	10139-05-6
Molecular Formula	C₅H₁₀N₂O₂
Molecular Weight	130.15 g/mol
Synonyms	(R)-2-Aminopiperidine-2-carboxylic acid; D-2-Aminopiperidine-2-carboxylic acid; D-1-Aminoproline; (R)-1-Aminoproline; D-1-Amino-proline; 1-Amino-D-proline; D-1-Amino-2-pyrrolidinecarboxylic acid; (2R)-2-Amino-2-piperidinecarboxylic acid
EINECS	Contact for details

Quality Control

Our D-Proline, 1-Amino- (9Ci) is produced under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral analysis to ensure enantiomeric excess and identity. Certificates of Analysis (COA) detailing all specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.