Description

Dansylcadaverine is a fluorescently labeled derivative of the polyamine cadaverine, widely recognized for its utility as a biochemical probe. Its core value lies in its strong fluorescence properties, which enable sensitive detection and quantification in complex biological systems. This compound is essential for researchers and manufacturers in the life sciences, particularly for applications in enzymology, cell biology, and diagnostic assay development.

Application

• Enzymatic Assay Substrate: Used as a specific fluorogenic substrate for transglutaminase (TGase) activity assays, crucial for research in celiac disease, cancer, and fibrosis.
• Biochemical Research Probe: Employed in fluorescence spectroscopy and microscopy to study polyamine transport, protein cross-linking, and post-translational modifications.
• Diagnostic Kit Component: Incorporated into in vitro diagnostic (IVD) kits for the detection and quantification of transglutaminase enzymes.
• Cell Labeling and Imaging: Utilized for fluorescent labeling of cells and tissues to visualize biological processes in real-time.
• Pharmaceutical R&D: Serves as a key reagent in high-throughput screening (HTS) for drug discovery programs targeting transglutaminase-related pathways.
• Quality Control in Biomanufacturing: Applied in QC labs to monitor enzyme activity during the production of biopharmaceuticals.

Basic Information

Product Name	Dansylcadaverine
CAS No.	10121-91-2
Molecular Formula	C17H23N3O2S
Molecular Weight	333.45 g/mol
Synonyms	5-((5-(Dimethylamino)naphthalen-1-yl)sulfonamido)pentan-1-amine; N-(5-Aminopentyl)-5-(dimethylamino)-1-naphthalenesulfonamide; Dansyl Cadav; DNC; DNS-Cadaverine; 1-Dimethylaminonaphthalene-5-sulfonylcadaverine; Nε-Dansyl-1,5-diaminopentane
EINECS	Contact for details

Quality Control

Our Dansylcadaverine is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity verification and spectroscopic methods for identity confirmation, to ensure it meets the high standards required for research and diagnostic applications. Certificates of Analysis (COA) with detailed specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is light-sensitive (store away from light). For long-term storage, consider desiccation to maintain stability.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Fluorescence Properties	Conforms (Ex/Em ~335/518 nm)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.