Description

Perphenazine Sulfoxide (100 Mg) is a high-purity pharmaceutical reference standard and key intermediate in the synthesis of neuroleptic agents. This compound is critical for quality control and research applications, ensuring the accuracy and reliability of analytical methods. It is primarily utilized by pharmaceutical R&D laboratories, quality assurance departments, and academic institutions focused on psychopharmacology and analytical chemistry development.

Application

• Pharmaceutical Reference Standard: Used for the identification, assay, and impurity profiling of Perphenazine and related drug substances in compliance with pharmacopeial methods (e.g., USP, EP).
• Active Pharmaceutical Ingredient (API) Intermediate: Serves as a crucial synthetic precursor in the manufacturing process of Perphenazine and its derivative formulations.
• Metabolite Studies: Employed in pharmacokinetic and metabolic pathway research to study the biotransformation of Perphenazine in biological systems.
• Analytical Method Development: Essential for developing and validating chromatographic (HPLC, GC) and spectroscopic methods in quality control laboratories.
• Impurity Standard: Used as a certified impurity standard to monitor and control the quality of Perphenazine bulk drug and finished dosage forms.
• Research Chemical: Applied in academic and industrial research investigating the structure-activity relationships of phenothiazine derivatives.

Basic Information

Product Name	Perphenazine Sulfoxide (100 Mg)
CAS No.	10078-25-8
Molecular Formula	C21H26ClN3O2S
Molecular Weight	419.97 g/mol
Synonyms	Perphenazine Sulfoxide; 1-[2-[4-[3-(2-Chloro-10H-phenothiazin-10-yl)propyl]piperazin-1-yl]ethoxy]ethanone S-Oxide; Perphenazine S-Oxide; 2-Chloro-10-[3-[4-(2-acetoxyethyl)piperazin-1-yl]propyl]phenothiazine 5-Oxide; NSC 138011; Perfenazine Sulfoxide
EINECS	Contact for details

Quality Control

Our Perphenazine Sulfoxide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identification by IR and NMR, purity assay by HPLC, and control of related substances. A Certificate of Analysis (COA) detailing all test results and specifications is provided with every shipment to ensure traceability and compliance with your research or quality control requirements.

Storage

Preserve in a tightly closed container, protected from light. Store under inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature of 15-25°C. The product is light-sensitive and easily oxidized; prolonged exposure to air, light, or elevated temperatures should be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.