Description

(R)-(+)-3-Methoxymandelonitrile is a high-purity chiral building block and synthetic intermediate of significant importance in asymmetric synthesis. Its value lies in its utility for constructing complex molecules with defined stereochemistry, which is critical for developing active pharmaceutical ingredients (APIs) and advanced agrochemicals. This compound is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries engaged in the production of enantiomerically pure substances.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of enantiomerically pure drugs, particularly in the development of β-blockers, antidepressants, and other bioactive molecules.
• Agrochemical Synthesis: Used in the production of chiral pesticides and herbicides where specific stereochemistry is required for optimal activity and environmental safety.
• Fine Chemical Production: Serves as a versatile building block for creating complex, high-value specialty chemicals and flavors & fragrances.
• Asymmetric Catalysis Research: Employed as a standard substrate or ligand precursor in academic and industrial research to develop new catalytic methodologies.
• Material Science: Potential use in the synthesis of chiral polymers or liquid crystals with specific optical properties.

Basic Information

Product Name	(R)-(+)-3-Methoxymandelonitrile
CAS No.	10049-65-7
Molecular Formula	C9H9NO2
Molecular Weight	163.17 g/mol
Synonyms	(R)-3-Methoxymandelonitrile; (R)-(+)-3-Methoxymandelic acid nitrile; (R)-α-Hydroxy-3-methoxybenzeneacetonitrile; (R)-2-Hydroxy-2-(3-methoxyphenyl)acetonitrile; (+)-3-Methoxymandelonitrile; (R)-O-Methylmandelonitrile; (R)-3-Methoxybenzaldehyde cyanohydrin
EINECS	233-164-6

Quality Control

Our (R)-(+)-3-Methoxymandelonitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for advanced synthetic applications. Certificates of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.