Description

(R)-(+)-3-Hydroxymandelonitrile is a high-value chiral building block and intermediate in organic synthesis. This compound matters for its role in the stereoselective production of complex molecules, particularly in the pharmaceutical sector. Industries that need it include pharmaceutical R&D, agrochemical manufacturing, and fine chemical synthesis for producing enantiomerically pure compounds.

Application

• Pharmaceutical Intermediate: Key chiral precursor for the synthesis of β-blockers, adrenergic agents, and other active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the production of enantiomerically pure herbicides and pesticides.
• Fine Chemical Building Block: Employed in asymmetric synthesis for creating complex natural products and specialty chemicals.
• Biochemical Research: Serves as a substrate or intermediate in enzymatic studies and metabolic pathway research.
• Chiral Catalyst & Ligand Development: Utilized in the research and development of novel asymmetric catalysts.
• Flavor & Fragrance Industry: Potential intermediate for the synthesis of specific chiral aroma compounds.

Basic Information

Product Name	(R)-(+)-3-Hydroxymandelonitrile
CAS No.	10049-64-6
Molecular Formula	C8H7NO2
Molecular Weight	149.15 g/mol
Synonyms	(R)-3-Hydroxymandelonitrile; (R)-(+)-3-Hydroxymandelonitrile; (R)-3-Hydroxy-2-hydroxybenzeneacetonitrile; (R)-3-Hydroxyphenylglycolonitrile; (R)-3-Hydroxybenzaldehyde cyanohydrin; (R)-3-Hydroxy-mandelic acid nitrile; (R)-3-Hydroxy-α-hydroxybenzeneacetonitrile; (R)-3-Hydroxymandelonitrile, (R)-enantiomer
EINECS	233-163-6

Quality Control

Our (R)-(+)-3-Hydroxymandelonitrile is produced under strict quality management systems to ensure batch-to-batch consistency and high enantiomeric purity. Products undergo rigorous analytical testing, including chiral HPLC, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing assay, enantiomeric excess, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is moisture-sensitive (hygroscopic) and should be handled under an inert atmosphere for prolonged storage to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.