Description

Gastrin I Human is a biologically active peptide hormone that plays a critical role in stimulating gastric acid secretion. This high-purity compound is essential for advanced research and development in endocrinology and gastroenterology. It is primarily utilized by pharmaceutical R&D teams, diagnostic manufacturers, and academic research institutions focusing on gastrointestinal physiology and related therapeutic areas.

Application

• Pharmaceutical Research & Development: Used as a reference standard and active ingredient in studies targeting gastric acid secretion disorders and the development of gastrointestinal therapeutics.
• Diagnostic Assay Development: Serves as a critical calibrant and control in immunoassays (e.g., ELISA, RIA) designed to measure gastrin levels for clinical diagnostics.
• Biochemical & Physiological Studies: Employed in in vitro and in vivo experiments to investigate the mechanisms of gastric secretion, hormone-receptor interactions, and digestive system signaling pathways.
• Cell Culture & Molecular Biology: Used to stimulate specific cellular responses in research models studying enteroendocrine cell function and hormone action.
• Quality Control & Standardization: Acts as a primary standard for the quality control of diagnostic kits and for the validation of analytical methods in regulatory environments.

Basic Information

Product Name	Gastrin I Human
CAS No.	10047-33-3
Molecular Formula	C97H124N20O31S
Molecular Weight	2098.2 g/mol
Synonyms	Human Gastrin I; Gastrin-17; G-17; HG-17; Little Gastrin; Gastrin I (human); Pyr-Leu-Gly-Pro-Gln-Gly-His-Pro-Ser-Leu-Val-Ala-Asp-Pro-Ser-Lys-Lys-Gln-Gly-Pro-Trp-Leu-Glu-Glu-Glu-Glu-Glu-Ala-Tyr-Gly-Trp-Met-Asp-Phe-NH2; L-Pyroglutamyl-L-leucylglycyl-L-prolyl-L-glutaminylglycyl-L-histidyl-L-prolyl-L-seryl-L-leucyl-L-valyl-L-alanyl-L-α-aspartyl-L-prolyl-L-seryl-L-lysyl-L-lysyl-L-glutaminylglycyl-L-prolyl-L-tryptophyl-L-leucyl-L-α-glutamyl-L-α-glutamyl-L-α-glutamyl-L-α-glutamyl-L-α-glutamyl-L-alanyl-L-tyrosylglycyl-L-tryptophyl-L-methionyl-L-α-aspartyl-L-phenylalaninamide
EINECS	233-149-7

Quality Control

Our Gastrin I Human is manufactured under strict quality systems to ensure batch-to-batch consistency and high biological activity. Each lot undergoes comprehensive analytical testing, including HPLC for purity, mass spectrometry for identity confirmation, and amino acid analysis. A detailed Certificate of Analysis (COA) documenting identity, purity, peptide content, and biological activity is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store desiccated at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a dry environment before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Peptide Content	≥ 80.0% (by amino acid analysis)
Single Impurity (HPLC)	≤ 1.0%
Water Content (Karl Fischer)	≤ 5.0%
Biological Activity	Assessed by in vitro bioassay; specific activity provided on COA

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.