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1,3,4,6-Tetra-o-Acetyl-2-Amino-2-Deoxy-A-D-Glucopyranose Hydrochloride CAS NO 10034-19-2
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CAS No.:10034-19-2
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
1,3,4,6-Tetra-o-Acetyl-2-Amino-2-Deoxy-A-D-Glucopyranose Hydrochloride is a key acetylated glycosyl donor and a vital protected intermediate in carbohydrate chemistry. This compound is essential for the controlled synthesis of complex oligosaccharides and glycoconjugates, offering high reactivity and stereoselectivity. It is primarily required by research institutions and pharmaceutical companies for the development of novel glycotherapeutics, vaccines, and diagnostic agents.
Application
- Glycosylation Reactions: Serves as a crucial building block for the stereoselective synthesis of oligosaccharides and glycans.
- Pharmaceutical Intermediates: Used in the research and production of glycosylated drugs, including antibiotics, antivirals, and anticancer agents.
- Glycoconjugate Vaccine Development: Acts as a key intermediate for attaching carbohydrate antigens to carrier proteins.
- Biochemical Research: Employed in enzymatic studies and the preparation of substrates for glycosyltransferases.
- Glycomimetics Synthesis: Used to create carbohydrate analogs for drug discovery targeting lectins and other carbohydrate-binding proteins.
- Diagnostic Reagent Production: A precursor for labeled sugars used in diagnostic assays and imaging probes.
Basic Information
| Product Name | 1,3,4,6-Tetra-o-Acetyl-2-Amino-2-Deoxy-A-D-Glucopyranose Hydrochloride |
| CAS No. | 10034-19-2 |
| Molecular Formula | C14H22ClNO9 |
| Molecular Weight | 383.78 g/mol |
| Synonyms | 2-Amino-2-deoxy-α-D-glucopyranose Hydrochloride Tetraacetate; N-Acetylglucosamine Tetraacetate Hydrochloride; Glucosamine Pentaacetate Hydrochloride; α-D-Glucosamine Tetraacetate Hydrochloride; 1,3,4,6-Tetra-O-acetyl-2-deoxy-2-amino-α-D-glucopyranose Hydrochloride; 2-Acetamido-1,3,4,6-tetra-O-acetyl-2-deoxy-α-D-glucopyranose Hydrochloride; Peracetylated Glucosamine Hydrochloride |
| EINECS | 233-101-8 |
Quality Control
Our 1,3,4,6-Tetra-o-Acetyl-2-Amino-2-Deoxy-A-D-Glucopyranose Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR, to ensure it meets exacting standards for research and pharmaceutical applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Identification (IR) | Conforms to structure |
| Identification (NMR) | Conforms to structure |
| Assay (HPLC) | ≥ 98.0% |
| Water Content (KF) | ≤ 1.0% |
| Specific Rotation [α]²⁰D | +100° to +110° (c=1 in CHCl₃) |
| Residue on Ignition | ≤ 0.1% |
| Heavy Metals | ≤ 20 ppm |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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