Description

[R,(+)]-2-Hydroxyhexanenitrile is a chiral, optically active nitrile derivative featuring a hydroxyl group at the alpha position. This compound serves as a valuable chiral building block and intermediate in the synthesis of complex organic molecules, particularly in the pharmaceutical and fine chemical industries. Its stereochemistry makes it essential for researchers and manufacturers developing enantiomerically pure active pharmaceutical ingredients (APIs), agrochemicals, and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the asymmetric synthesis of β-amino alcohols, amino acids, and other bioactive molecules.
• Agrochemical Synthesis: Used in the production of enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Fine Chemical Production: Serves as a precursor for flavors, fragrances, and advanced material monomers requiring specific chirality.
• Asymmetric Catalysis Research: Employed as a substrate or ligand precursor in the development and testing of new chiral catalysts.
• Chemical Biology & Proteomics: Can be utilized in the synthesis of activity-based probes or molecular tags for studying enzyme function.

Basic Information

Product Name	[R,(+)]-2-Hydroxyhexanenitrile
CAS No.	10021-65-5
Molecular Formula	C₆H₁₁NO
Molecular Weight	113.16 g/mol
Synonyms	(R)-(+)-2-Hydroxyhexanenitrile; (R)-2-Hydroxycapronitrile; D-(+)-2-Hydroxyhexanenitrile; (R)-2-Hydroxyhexanenitrile; (2R)-2-Hydroxyhexanenitrile; (+)-2-Hydroxyhexanenitrile; (R)-α-Hydroxyhexanenitrile; 2-Hydroxyhexanenitrile, (R)-(+)-
EINECS	233-008-4

Quality Control

Our [R,(+)]-2-Hydroxyhexanenitrile is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for synthetic applications. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and enantiomeric excess.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents, strong acids, and strong bases.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.