Description

(R)-2-Hydroxypentanenitrile is a chiral nitrile compound featuring a hydroxyl group on the alpha carbon. This specific enantiomer is a valuable chiral building block and intermediate in asymmetric synthesis, enabling the production of optically active pharmaceuticals and fine chemicals. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of enantiomerically pure active pharmaceutical ingredients (APIs), particularly in neurological and cardiovascular drug research.
• Agrochemical Synthesis: Used in the production of chiral pesticides and herbicides, where the specific stereochemistry can be critical for biological activity and environmental safety.
• Fine Chemical Production: Serves as a precursor for flavors, fragrances, and other high-value specialty chemicals requiring defined stereochemistry.
• Asymmetric Catalysis Research: Employed as a substrate or ligand precursor in academic and industrial research to develop new catalytic methodologies.
• Material Science: Potential monomer or modifier for creating polymers with specific chiral properties for advanced material applications.

Basic Information

Product Name	(R)-2-Hydroxypentanenitrile
CAS No.	10021-63-3
Molecular Formula	C5H9NO
Molecular Weight	99.13 g/mol
Synonyms	(R)-2-Hydroxyvaleronitrile; (R)-2-Hydroxypentanenitrile; (R)-2-Hydroxybutyronitrile, 2-Methyl-; (R)-α-Hydroxybutyronitrile; (2R)-2-Hydroxypentanenitrile; D-2-Hydroxypentanenitrile; (R)-1-Cyano-1-butanol
EINECS	233-009-4

Quality Control

Our (R)-2-Hydroxypentanenitrile is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and enantiomeric excess are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). This compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere if specified.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.