Description

H-Orn(Pht)-Oh Hcl is a protected derivative of the amino acid ornithine, where the side-chain amine is shielded by a phthaloyl (Pht) group. This compound is a critical building block in peptide synthesis and pharmaceutical research, offering precise control over molecular structure. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors for developing novel therapeutic agents and complex organic molecules.

Application

• Peptide Synthesis: Serves as a key protected intermediate for the solid-phase and solution-phase synthesis of peptides containing ornithine.
• Pharmaceutical Intermediates: Used in the research and development of active pharmaceutical ingredients (APIs) and prodrugs.
• Bioconjugation: Acts as a linker or spacer molecule in the conjugation of peptides to other biomolecules or surfaces.
• Chemical Biology Research: Employed in studies investigating protein-protein interactions and enzyme mechanisms.
• Fine Chemical Production: A valuable precursor for the manufacture of specialized catalysts and chiral auxiliaries.

Basic Information

Product Name	H-Orn(Pht)-Oh Hcl
CAS No.	10009-97-9
Molecular Formula	C13H15N2O4•HCl
Molecular Weight	308.73 g/mol
Synonyms	Nδ-Phthaloyl-L-ornithine hydrochloride; (S)-2-Amino-5-(1,3-dioxoisoindolin-2-yl)pentanoic acid hydrochloride; L-Ornithine, N5-phthaloyl-, hydrochloride; Phthaloylornithine hydrochloride; H-Orn(Pht)-OH•HCl; N5-Phthaloyl-L-ornithine HCl; Fmoc-Orn(Pht)-OH precursor
EINECS	Contact for details

Quality Control

Our H-Orn(Pht)-Oh Hcl is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation, to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) with detailed specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Assay (HPLC)	≥98.0%
Optical Rotation	[α]D20: Specific range provided on COA
Water Content (KF)	≤1.0%
Heavy Metals	≤20 ppm
Residual Solvents	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.