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(S)-2-Amino-3-(4-Bromophenyl)Propanoic Acid CAS NO 1991-80-6
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CAS No.:1991-80-6
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
(S)-2-Amino-3-(4-Bromophenyl)Propanoic Acid is a high-purity, non-natural amino acid derivative featuring a chiral center and a brominated aromatic side chain. This compound is a critical chiral building block for the synthesis of complex molecules, offering precise stereochemical control. It is primarily utilized by research institutions and pharmaceutical companies engaged in drug discovery, peptide chemistry, and the development of enzyme inhibitors.
Application
- Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel active pharmaceutical ingredients (APIs), particularly in oncology and CNS drug candidates.
- Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis to incorporate a bromophenylalanine analogue, modifying peptide properties for structure-activity relationship (SAR) studies.
- Biochemical Research: Serves as a substrate or inhibitor in enzymatic studies and as a precursor for fluorescent or radiolabeled probes in biological assays.
- Organocatalyst & Ligand Development: Employed in the design and synthesis of chiral catalysts and ligands for asymmetric synthesis.
- Material Science: A potential monomer for constructing specialized polymers with unique optical or electronic properties.
Basic Information
| Product Name | (S)-2-Amino-3-(4-Bromophenyl)Propanoic Acid |
| CAS No. | 1991-80-6 |
| Molecular Formula | C9H10BrNO2 |
| Molecular Weight | 244.09 g/mol |
| Synonyms | (S)-4-Bromophenylalanine; (S)-p-Bromophenylalanine; (S)-2-Amino-3-(4-bromophenyl)propionic acid; L-4-Bromophenylalanine; (S)-3-(4-Bromophenyl)alanine; H-(4-Br-Phe)-OH; BOC-(S)-4-Bromo-Phe-OH (protected form); Fmoc-(S)-4-Bromo-Phe-OH (protected form) |
| EINECS | Contact for details |
Quality Control
Our (S)-2-Amino-3-(4-Bromophenyl)Propanoic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) detailing purity, chiral excess, and impurity profiles are available for every lot upon request.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Identification (IR) | Conforms to structure |
| Assay (HPLC) | ≥98.0% |
| Chiral Purity (HPLC) | ≥99.0% ee |
| Loss on Drying | ≤0.5% |
| Residue on Ignition | ≤0.1% |
| Heavy Metals | ≤10 ppm |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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