Description

2',5'-Difluoroacetophenone is a high-purity fluorinated aromatic ketone building block, essential for advanced organic synthesis. This compound is valued for its role in introducing difluorophenyl motifs, which are critical for modulating the physicochemical and metabolic properties of target molecules. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly those targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Synthesis: Used in the production of advanced herbicides and pesticides, where the fluorine atoms enhance biological activity and environmental stability.
• Liquid Crystal Materials: Serves as a precursor in the synthesis of fluorinated compounds for electronic display applications.
• Organic Light-Emitting Diodes (OLEDs): Employed in the development of electron-transport and host materials for efficient OLED devices.
• Advanced Material Research: Utilized as a building block for polymers and coatings with specific thermal and chemical resistance properties.
• Chemical Research & Development: A versatile reagent for method development and exploring new fluorination chemistry in academic and industrial labs.

Basic Information

Product Name	2',5'-Difluoroacetophenone
CAS No.	1979-36-8
Molecular Formula	C8H6F2O
Molecular Weight	156.13 g/mol
Synonyms	1-(2,5-Difluorophenyl)ethanone; 2,5-Difluoroacetophenone; 2',5'-Difluoroacetophenone; 2,5-Difluorophenyl methyl ketone; Ethanone, 1-(2,5-difluorophenyl)-; α,2,5-Trifluoroacetophenone (incorrect but common alias); 2,5-DFAP
EINECS	217-829-6

Quality Control

Every batch of 2',5'-Difluoroacetophenone is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the product meets the high-purity standards required for sensitive synthetic applications. A detailed Certificate of Analysis (COA) is supplied with each shipment, confirming specifications for identity, purity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong bases and reducing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.