Description

(4-Fluorophenyl)(Morpholino)Methanone is a high-value organic building block featuring both a fluorinated aromatic ring and a morpholine moiety. This bifunctional structure makes it a critical intermediate in the synthesis of advanced pharmaceutical compounds and agrochemicals. It is primarily sought after by R&D chemists and process development scientists in the life sciences sector for constructing complex molecules with targeted biological activity.

Application

• Pharmaceutical Intermediate: A key synthon in the development of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors, CNS agents, and anti-inflammatory drugs.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides, leveraging the bioactivity of the fluorophenyl group.
• Material Science Research: Serves as a precursor for specialty polymers and liquid crystals, where the morpholine group can impart specific solubility or mesogenic properties.
• Chemical Biology & Proteomics: Employed as a scaffold or linker in the design of molecular probes and enzyme inhibitors for biochemical research.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for use in multi-step custom synthesis projects for clients in various industries.

Basic Information

Product Name	(4-Fluorophenyl)(Morpholino)Methanone
CAS No.	1978-65-0
Molecular Formula	C11H12FNO2
Molecular Weight	209.22 g/mol
Synonyms	4-Fluorobenzoyl morpholine; Morpholino 4-fluorophenyl ketone; 1-(4-Fluorobenzoyl)morpholine; 4-Fluorophenyl morpholino ketone; N-(4-Fluorobenzoyl)morpholine; 4-Fluorobenzoic acid morpholide; 4-Fluorophenyl(morpholino)methanone
EINECS	217-829-7

Quality Control

Every batch of (4-Fluorophenyl)(Morpholino)Methanone is manufactured under strict quality management systems. We provide comprehensive analytical data to ensure the material meets the stringent requirements for pharmaceutical and advanced chemical synthesis. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Melting Point	92 - 96 °C
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Related Substances (HPLC)	Total impurities ≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.