Description

Loxapine CAS NO 1977-10-2 is a dibenzoxazepine-class tricyclic compound primarily recognized for its antipsychotic properties. It is a critical active pharmaceutical ingredient (API) used in the formulation of medications for the management of schizophrenia and other psychotic disorders. This high-purity compound is essential for pharmaceutical manufacturers and research institutions focused on central nervous system therapeutics. Our supply ensures consistent quality and reliable availability for global production and development needs.

Application

• Primary use as an Active Pharmaceutical Ingredient (API) in the manufacture of antipsychotic medications.
• Formulation of oral dosage forms such as tablets and capsules for the treatment of schizophrenia.
• Research and development of novel drug delivery systems, including potential inhalation powders.
• Chemical reference standard for analytical testing and quality control in pharmaceutical laboratories.
• Preclinical and clinical research studies investigating neurological pathways and drug efficacy.
• Starting material or intermediate in the synthesis of more complex pharmaceutical compounds.

Basic Information

Product Name	Loxapine
CAS No.	1977-10-2
Molecular Formula	C18H18ClN3O
Molecular Weight	327.81 g/mol
Synonyms	Loxapine; Loxapine Base; 2-Chloro-11-(4-methyl-1-piperazinyl)dibenz[b,f][1,4]oxazepine; Oxilapine; CL-71563; Loxapac; Loxitane; Sumilap; Daxolin; Desconex; Loxapin; Loxapinum
EINECS	217-852-9

Quality Control

Our Loxapine is manufactured under strict quality management systems to meet the rigorous standards of the pharmaceutical industry. Every batch is subjected to comprehensive analytical testing, including identification, purity assay, and impurity profiling via advanced techniques like HPLC. A Certificate of Analysis (COA) is provided with each shipment, detailing compliance with in-house specifications. We support compliance with major pharmacopeial guidelines (e.g., USP, EP) and regulatory frameworks such as ICH Q7.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials. The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference standard
Identification (HPLC)	Retention time matches reference
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.