Description

2-Chloro-11-(4-Methyl-1-Piperazinyl)-5H-Dibenzo(B,E)(1,4)Diazepine is a high-purity pharmaceutical intermediate of significant commercial and research interest. This compound is valued for its role as a key synthetic precursor in the development of active pharmaceutical ingredients (APIs). It is primarily sought by manufacturers and R&D facilities in the pharmaceutical and fine chemical sectors engaged in the synthesis of complex heterocyclic molecules. The product is supplied with a commitment to stringent quality control and supply chain reliability.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of tricyclic psychoactive compounds and related therapeutic agents.
• Active Pharmaceutical Ingredient (API) Development: Used in research and process development for novel central nervous system (CNS) targeting drugs.
• Chemical Reference Standard: Serves as a high-purity analytical standard for quality control and method validation in pharmaceutical laboratories.
• Medicinal Chemistry Research: A valuable scaffold for structure-activity relationship (SAR) studies and the discovery of new bioactive molecules.
• Fine Chemical Synthesis: Employed in custom synthesis and contract manufacturing of complex, high-value specialty chemicals.

Basic Information

Product Name	2-Chloro-11-(4-Methyl-1-Piperazinyl)-5H-Dibenzo(B,E)(1,4)Diazepine
CAS No.	1977-08-8
Molecular Formula	C18H19ClN4
Molecular Weight	326.82 g/mol
Synonyms	Clozapine Impurity; 2-Chloro-11-(4-methylpiperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine; 8-Chloro-11-(4-methyl-1-piperazinyl)-5H-dibenzo[b,e][1,4]diazepine; Clozapine Related Compound; Norclozapine Impurity; Desmethylclozapine Impurity; 2-Chloro-11-(4-methylpiperazino)dibenz[b,f][1,4]oxazepine (obsolete); DBZP derivative
EINECS	Contact for details

Quality Control

Our 2-Chloro-11-(4-Methyl-1-Piperazinyl)-5H-Dibenzo(B,E)(1,4)Diazepine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for pharmaceutical intermediate applications. Certificates of Analysis (COA) detailing all specifications and test results are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Individual impurity ≤ 0.5%
Total Impurities	≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.