Description

5-Benzyloxytryptophan is a protected derivative of the essential amino acid tryptophan, featuring a benzyloxy group on the indole ring. This modification is critical for its primary role as a key chiral building block and advanced pharmaceutical intermediate in the synthesis of complex bioactive molecules. It is essential for research and production in the pharmaceutical and biotechnology sectors, particularly for developing peptide-based therapeutics, neuroactive compounds, and other high-value fine chemicals.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of peptide drugs, enzyme inhibitors, and other active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a specialized reagent in neuroscience and metabolic pathway studies, particularly those involving serotonin and melatonin analogs.
• Peptide Synthesis: Serves as a protected tryptophan derivative in solid-phase and solution-phase peptide synthesis (SPPS) to prevent side reactions.
• Asymmetric Synthesis: Employed as a chiral pool starting material for the construction of complex natural products and enantiomerically pure compounds.
• Reference Standard: Utilized as an analytical standard in quality control laboratories for method development and validation.

Basic Information

Product Name	5-Benzyloxytryptophan
CAS No.	1956-25-8
Molecular Formula	C18H18N2O3
Molecular Weight	310.35 g/mol
Synonyms	5-O-Benzyl-L-tryptophan; (S)-2-Amino-3-(5-(benzyloxy)-1H-indol-3-yl)propanoic acid; L-5-Benzyloxytryptophan; 5-Benzyloxy-DL-tryptophan; 5-Benzyloxyindole-3-alanine; Bzl-O-Trp; 5-BzlO-Trp; 5-(Benzyloxy)tryptophan
EINECS	Contact for details

Quality Control

Our 5-Benzyloxytryptophan is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical R&D and production. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and specific impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% (L-isomer)
Loss on Drying	≤1.0%
Residue on Ignition	≤0.5%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.