Description

Metrizoic Acid CAS NO 1949-45-7 is an iodinated organic compound belonging to the class of triiodobenzoic acid derivatives. This compound is valued for its role as a key intermediate in the synthesis of iodinated contrast media used in diagnostic imaging. It is primarily required by manufacturers in the pharmaceutical and fine chemical sectors for producing X-ray and CT scan contrast agents. Its specific chemical structure is critical for achieving the desired radiopacity and pharmacokinetic properties in final formulations.

Application

• Pharmaceutical Intermediate: Primary use as a building block for synthesizing non-ionic, low-osmolar iodinated contrast agents like Metrizamide.
• Diagnostic Imaging: Essential in the production of contrast media for myelography, angiography, and computed tomography (CT) scans.
• Research & Development: Used in biochemical and pharmacological research to study contrast agent mechanisms and develop new diagnostic compounds.
• Fine Chemical Synthesis: Serves as a specialized intermediate in custom synthesis and process development for advanced organic molecules.

Basic Information

Product Name	Metrizoic Acid
CAS No.	1949-45-7
Molecular Formula	C12H11I3N2O4
Molecular Weight	627.94 g/mol
Synonyms	3-Acetamido-2,4,6-triiodo-5-(N-methylacetamido)benzoic Acid; Ametrizoic Acid; NSC 112931; 5-(N-Methylacetamido)-2,4,6-triiodo-3-acetamidobenzoic Acid; 2,4,6-Triiodo-3-acetamido-5-N-methylacetamidobenzoic Acid; Metrizoate; Acidum Ametrizoicum
EINECS	217-773-6

Quality Control

Our Metrizoic Acid is manufactured under a strict quality management system. Each batch is tested to ensure it meets high-purity standards suitable for pharmaceutical intermediate applications. We provide comprehensive Certificates of Analysis (COA) detailing identity, purity, and impurity profiles. Our quality commitment aligns with cGMP principles for active pharmaceutical ingredient (API) intermediates, ensuring traceability and consistency for our global customers.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.