Description

2,4,6-Triiodo-3,5-Bis(n-Methylacetamido)Benzoic Acid is a specialized iodinated organic compound with a complex molecular structure, serving as a critical intermediate in advanced chemical synthesis. Its primary value lies in its role as a precursor for X-ray contrast media and other diagnostic agents, where its high iodine content is essential for effective imaging. This product is vital for pharmaceutical R&D laboratories and manufacturers focused on developing non-ionic, low-osmolar contrast agents for medical diagnostics.

Application

• Key Intermediate for X-ray Contrast Media: Primary building block in the synthesis of iopamidol, ioversol, and related non-ionic contrast agents.
• Pharmaceutical Research & Development: Used in the discovery and process development of new diagnostic imaging compounds.
• Active Pharmaceutical Ingredient (API) Synthesis: Serves as a core structural component in the manufacturing of final drug substances.
• Radiology & Diagnostic Imaging: Contributes to the production of agents for computed tomography (CT), angiography, and urography.
• Chemical Reference Standard: Utilized as a high-purity standard for analytical method development and quality control in pharmaceutical labs.
• Specialty Organic Synthesis: Employed in research for creating novel iodinated molecules with potential biological activity.

Basic Information

Product Name	2,4,6-Triiodo-3,5-Bis(n-Methylacetamido)Benzoic Acid
CAS No.	1949-44-6
Molecular Formula	C13H13I3N2O4
Molecular Weight	649.97 g/mol
Synonyms	3,5-Bis(acetylmethylamino)-2,4,6-triiodobenzoic Acid; 2,4,6-Triiodo-3,5-bis[(N-methylacetamido)]benzoic Acid; Iopamidol Intermediate; Ioversol Intermediate; WIN 39424; NSC 113994; Benzoic acid, 2,4,6-triiodo-3,5-bis[(N-methylacetamido)]-
EINECS	Contact for details

Quality Control

Our 2,4,6-Triiodo-3,5-Bis(n-Methylacetamido)Benzoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the exacting standards required for pharmaceutical intermediate applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment. We support compliance with cGMP and ICH guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Single Maximum Impurity	≤0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Heavy Metals	≤20 ppm
Loss on Drying	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.