Description

4-tert-Butyl n-[(tert-Butoxy)Carbonyl]-L-Aspartate Dicyclohexylamine Salt is a high-purity, protected aspartic acid derivative primarily used as a critical building block in peptide synthesis. This compound is essential for researchers and manufacturers requiring precise control over amino acid side-chain functionality during complex peptide assembly. It is particularly valuable for the pharmaceutical and biotechnology industries in the development of therapeutic peptides, APIs, and advanced research compounds.

Application

• Pharmaceutical Intermediate: A key protected amino acid derivative for the solid-phase and solution-phase synthesis of therapeutic peptides and proteins.
• API Synthesis: Used in the manufacturing process of Active Pharmaceutical Ingredients (APIs) that contain aspartic acid or require its specific properties.
• Bioconjugation & Labeling: Serves as a precursor for creating modified amino acids used in bioconjugation strategies for drug delivery systems or diagnostic agents.
• Research & Development: An essential reagent in academic and industrial R&D for exploring new peptide-based drug candidates and studying protein structure-function relationships.
• Custom Peptide Production: Employed by CROs and CDMOs for the custom synthesis of complex, non-standard peptides for clients.
• Protecting Group Strategy: The tert-butyl and Boc protecting groups allow for orthogonal deprotection, enabling sophisticated, multi-step synthetic routes.

Basic Information

Product Name	4-tert-Butyl n-[(tert-Butoxy)Carbonyl]-L-Aspartate Dicyclohexylamine Salt
CAS No.	1913-12-8
Molecular Formula	C23H44N2O6
Molecular Weight	444.61 g/mol
Synonyms	L-Aspartic acid, N-[(1,1-dimethylethoxy)carbonyl]-, 4-(1,1-dimethylethyl) ester, compd. with N-cyclohexylcyclohexanamine (1:1); Boc-L-Asp(OtBu)-OH·DCHA salt; N-Boc-L-aspartic acid 4-tert-butyl ester dicyclohexylamine salt; Nα-Boc-L-aspartic acid β-tert-butyl ester dicyclohexylammonium salt; Boc-Asp(OtBu)-OH DCHA salt; tert-Butyl N-(tert-butoxycarbonyl)-L-aspartate dicyclohexylamine salt; (2S)-2-[(tert-Butoxycarbonyl)amino]butanedioic acid 4-tert-butyl ester dicyclohexylamine salt
EINECS	Contact for details

Quality Control

Our 4-tert-Butyl n-[(tert-Butoxy)Carbonyl]-L-Aspartate Dicyclohexylamine Salt is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure it meets the high-purity standards required for pharmaceutical and research applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity (by HPLC), chiral purity, and related substances is provided with each shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry conditions to prevent degradation. For long-term storage, consider using a desiccant in the storage environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% (L-isomer)
Related Substances (HPLC)	Total impurities ≤2.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.