Description

3-(p-Fluorophenyl)-2-Methyl-4(3H)-Quinazolinon is a high-purity, fluorinated quinazolinone derivative, a key heterocyclic building block valued for its role in advanced organic synthesis. This compound is essential for research and development in the pharmaceutical and agrochemical sectors, where its unique structure enables the creation of novel active ingredients. It is primarily sought by fine chemical manufacturers, contract research organizations (CROs), and academic institutions focused on medicinal chemistry and material science.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders, anti-inflammatory agents, and kinase inhibitors.
• Agrochemical Research: Serves as a core scaffold for developing new herbicides, fungicides, and insecticides, leveraging the bioactivity of the quinazolinone moiety.
• Material Science: Used in the research of advanced organic materials, including organic light-emitting diodes (OLEDs) and liquid crystals, due to its fluorinated aromatic system.
• Academic & R&D: A valuable reagent for methodological studies in organic chemistry, such as novel cross-coupling reactions and heterocycle formation.
• Chemical Reference Standard: Employed as an analytical standard in quality control laboratories for method development and validation.

Basic Information

Product Name	3-(p-Fluorophenyl)-2-Methyl-4(3H)-Quinazolinon
CAS No.	1897-80-9
Molecular Formula	C15H11FN2O
Molecular Weight	254.26 g/mol
Synonyms	3-(4-Fluorophenyl)-2-methyl-4(3H)-quinazolinone; 2-Methyl-3-(4-fluorophenyl)-4(3H)-quinazolinone; 4(3H)-Quinazolinone, 3-(4-fluorophenyl)-2-methyl-; 3-(p-Fluorophenyl)-2-methylquinazolin-4(3H)-one; 1897-80-9; NSC 406170; p-Fluorophenyl-2-methyl-4-quinazolinone
EINECS	Contact for details

Quality Control

Our 3-(p-Fluorophenyl)-2-Methyl-4(3H)-Quinazolinon is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR/IR for structural confirmation, to ensure it meets the high standards required for research and synthesis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.