Description

Acetamide, 2,2,2-Trifluoro-n-(2-Mercaptoethyl)- is a specialized organofluorine compound that serves as a critical building block in advanced chemical synthesis. Its unique structure, featuring both a trifluoroacetamide group and a terminal thiol, makes it a versatile intermediate for introducing fluorine and sulfur functionalities into target molecules. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical sectors developing novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of fluorinated drug candidates, particularly those targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the development of advanced herbicides and fungicides, where the fluorine atom enhances biological activity and environmental stability.
• Ligand and Chelator Preparation: Serves as a starting material for synthesizing specialized ligands used in catalysis and metal ion chelation.
• Peptide Modification: Employed to introduce fluorinated motifs and thiol-reactive handles into peptides and bioconjugates.
• Material Science Research: Utilized in creating functionalized surfaces and polymers with specific adhesion or reactivity properties.
• Cross-linking Agent: Acts as a bifunctional linker in polymer chemistry and for the modification of biomolecules.

Basic Information

Product Name	Acetamide, 2,2,2-Trifluoro-n-(2-Mercaptoethyl)-
CAS No.	1869-45-0
Molecular Formula	C4H6F3NOS
Molecular Weight	173.16 g/mol
Synonyms	N-(2-Mercaptoethyl)-2,2,2-trifluoroacetamide; 2,2,2-Trifluoro-N-(2-sulfanylethyl)acetamide; 2,2,2-Trifluoroacetothioamide, N-(2-hydroxyethyl)-; TFMEA; 2-(Trifluoroacetamido)ethanethiol; 1-(Trifluoroacetyl)thioethylamine; 2-Mercaptoethyl trifluoroacetamide; TFA-thioethylamide
EINECS	Contact for details

Quality Control

Our Acetamide, 2,2,2-Trifluoro-n-(2-Mercaptoethyl)- is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and commercial synthesis. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to the presence of a thiol group, ensure the container is sealed under an inert atmosphere (e.g., nitrogen) for long-term storage to prevent oxidation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.