Description

Difluorosulfoacetic Acid Dimethyl Ester is a specialized fluorinated and sulfonated building block of significant interest in advanced chemical synthesis. This compound matters for its unique molecular architecture, which combines a reactive sulfonyl fluoride moiety with an ester group, enabling its use in the creation of complex, high-value molecules. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for applications such as the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, particularly those requiring sulfonyl fluoride or difluoroacetate motifs.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides with enhanced properties.
• Material Science: Serves as a monomer or cross-linking agent in the development of specialty polymers and advanced functional materials.
• Chemical Biology Probe Development: Utilized in creating activity-based probes (ABPs) that target serine hydrolases and other enzymes due to its sulfonyl fluoride electrophile.
• Organic Synthesis Reagent: Acts as a versatile reagent for introducing difluorosulfonyl and ester functionalities into target molecules under controlled conditions.
• Ligand and Catalyst Preparation: Employed in the synthesis of specialized ligands and organometallic catalysts for asymmetric catalysis.

Basic Information

Product Name	Difluorosulfoacetic Acid Dimethyl Ester
CAS No.	1869-42-7
Molecular Formula	C4H6F2O4S
Molecular Weight	188.15 g/mol
Synonyms	Dimethyl Difluorosulfoacetate; Acetic Acid, Difluorosulfo-, Dimethyl Ester; Difluorosulfonylacetic Acid Dimethyl Ester; Methyl 2-(Difluorosulfonyl)acetate; 2-(Difluorosulfonyl)acetic Acid Methyl Ester; Dimethyl (Difluorosulfonyl)acetate; DFSA-DME
EINECS	Contact for details

Quality Control

Our Difluorosulfoacetic Acid Dimethyl Ester is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including chromatography and spectroscopy, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee compliance with your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong bases and oxidizing agents. Due to its nature as a strong acid/organic solvent, handle with appropriate engineering controls and personal protective equipment. Recommended long-term storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.