Description

Z-Arg-Betana Hcl is a protected arginine derivative, specifically the benzyloxycarbonyl (Z) protected form of arginine betaine hydrochloride. This compound is a crucial building block in peptide synthesis, offering a protected guanidino group that is stable under standard coupling conditions. It is primarily utilized by researchers and manufacturers in the pharmaceutical and biotechnology sectors for the development of novel therapeutic peptides and biochemical probes.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key intermediate for the controlled incorporation of arginine residues into peptide chains.
• Solution-Phase Peptide Chemistry: Used in the synthesis of complex peptides and peptidomimetics where solution-phase strategies are preferred.
• Bioconjugation: Serves as a modified amino acid precursor for labeling peptides or creating peptide-based conjugates for diagnostic or targeting applications.
• Pharmaceutical Research: Employed in the R&D of peptide-based drugs targeting various diseases, including cardiovascular and metabolic disorders.
• Biochemical Tool Development: Used to synthesize substrates or inhibitors for enzymes like trypsin-like proteases or nitric oxide synthases.
• Academic Research: A fundamental reagent in university and institutional labs studying protein-protein interactions, signal transduction, and peptide structure-activity relationships.

Basic Information

Product Name	Z-Arg-Betana Hcl
CAS No.	1851-28-1
Molecular Formula	C15H23N5O4 • HCl
Molecular Weight	381.84 g/mol
Synonyms	Nα-Benzyloxycarbonyl-Nω-[(tert-butoxy)carbonyl]-L-arginine hydrochloride; Z-Arg(Boc)-OH • HCl; Nα-Cbz-Nω-Boc-L-arginine hydrochloride; Benzyl N-[(1S)-5-[(tert-butoxycarbonyl)amino]-1-carboxy-4-guanidinopentyl]carbamate hydrochloride; Cbz-Arg(Boc)-OH • HCl; Z-L-arginine(Boc)-OH hydrochloride; Nα-Z-Nω-Boc-L-arginine hydrochloride
EINECS	Contact for details

Quality Control

Our Z-Arg-Betana Hcl is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and cGMP applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis for enantiomeric excess, and identity confirmation. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting compliance with specified standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Optical Rotation	[α]D20: Contact for details
Water Content (KF)	≤1.0%
Heavy Metals	≤20 ppm
Residual Solvents	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.