Description

Fluspirilene is a potent, long-acting diphenylbutylpiperidine-class antipsychotic agent. Its primary value lies in its extended duration of action, which is critical for ensuring consistent therapeutic management. This compound is essential for pharmaceutical R&D and manufacturing, particularly in the development of depot formulations for treating chronic psychiatric conditions such as schizophrenia. Fluspirilene CAS NO 1841-19-6 is a key intermediate and active pharmaceutical ingredient (API) for global healthcare suppliers.

Application

• Pharmaceutical Active Ingredient (API): Primary use in the formulation of long-acting injectable antipsychotic medications.
• Reference Standard: Serves as a critical analytical standard in quality control laboratories for method development and validation.
• Research & Development: Used in preclinical and clinical studies to investigate the pharmacology and efficacy of antipsychotic agents.
• Drug Substance Manufacturing: A key chemical entity for pharmaceutical companies synthesizing neuroleptic drugs.
• Pharmacopoeial Standards: Material suitable for use in conjunction with monographs from pharmacopoeias such as USP or EP.
• Biochemical Research: Tool compound for studying dopamine D2 receptor antagonism and related neurological pathways.

Basic Information

Product Name	Fluspirilene
CAS No.	1841-19-6
Molecular Formula	C₂₉H₃₁F₂N₃O
Molecular Weight	475.57 g/mol
Synonyms	8-[4,4-Bis(4-fluorophenyl)butyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one; R 6218; Imap; Redeptin; Fluspiperone; Fluspirilen; Fluspiriline; Fluspinilene
EINECS	217-419-4

Quality Control

Our Fluspirilene is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including identity confirmation, purity assay, and impurity profiling via advanced techniques like HPLC and GC. We provide full traceability and Certificates of Analysis (COA) that detail compliance with in-house specifications. Material can be supplied to meet the requirements of current Good Manufacturing Practice (cGMP) for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Any single unknown impurity	≤0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤0.5%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.