Description

n-Tfa-Dl-Methionine Methyl Ester is a protected derivative of the essential amino acid methionine, widely used as a key chiral building block in organic synthesis. Its primary value lies in providing a reactive ester group and a trifluoroacetyl (Tfa) protecting group, which facilitates selective peptide coupling and subsequent deprotection under mild conditions. This compound is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and advanced materials sectors, particularly for the synthesis of peptides, peptidomimetics, and other bioactive molecules.

Application

• Peptide Synthesis: A crucial intermediate for the solid-phase and solution-phase synthesis of complex peptides and proteins.
• Pharmaceutical Intermediates: Serves as a key chiral building block in the production of active pharmaceutical ingredients (APIs) and drug candidates.
• Bioconjugation: Used in the modification of biomolecules for drug delivery systems, diagnostics, and biochemical probes.
• Research & Development: A valuable reagent in academic and industrial R&D labs for exploring new synthetic methodologies and creating novel compounds.
• Amino Acid Derivative Production: Acts as a precursor for other specialized, protected methionine derivatives with tailored functionalities.

Basic Information

Product Name	n-Tfa-Dl-Methionine Methyl Ester
CAS No.	1808-40-8
Molecular Formula	C9H14F3NO4S
Molecular Weight	289.27 g/mol
Synonyms	DL-Methionine, N-(Trifluoroacetyl)-, Methyl Ester; Methyl N-(Trifluoroacetyl)-DL-methioninate; N-Trifluoroacetyl-DL-methionine Methyl Ester; TFA-DL-Met-OMe; Methionine, N-trifluoroacetyl-, methyl ester, DL-; Methyl 2-[(trifluoroacetyl)amino]-4-(methylsulfanyl)butanoate
EINECS	Contact for details

Quality Control

Our n-Tfa-Dl-Methionine Methyl Ester is produced under stringent quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) for every batch, detailing key parameters such as assay, chiral purity, and impurity profiles. Our quality commitment aligns with the standards required for fine chemical and pharmaceutical intermediate applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity	DL-mixture (Racemic)
Melting Point	Contact for details
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.