Description

3-(Trifluoromethyl)Benzamide is a high-purity fluorinated aromatic building block of significant interest in advanced chemical synthesis. This compound matters for its role as a key intermediate in the development of active pharmaceutical ingredients (APIs) and agrochemicals, where the trifluoromethyl group is prized for its ability to modulate lipophilicity and metabolic stability. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to incorporate this valuable pharmacophore into novel molecules.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel drug candidates, particularly in oncology, CNS, and anti-inflammatory therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides that benefit from the properties of the CF3 group.
• Material Science Research: Serves as a monomer or precursor for developing specialty polymers and liquid crystals with unique optical or electronic properties.
• Organic Synthesis & Catalysis: Employed in cross-coupling reactions and as a ligand precursor in catalytic systems for complex molecule construction.
• Fluorine Chemistry Studies: A valuable reference compound for academic and industrial research into the behavior and reactivity of aromatic fluorinated systems.

Basic Information

Product Name	3-(Trifluoromethyl)Benzamide
CAS No.	1801-10-1
Molecular Formula	C8H6F3NO
Molecular Weight	189.14 g/mol
Synonyms	m-(Trifluoromethyl)benzamide; 3-(Trifluoromethyl)benzenecarboxamide; α,α,α-Trifluoro-m-toluamide; Benzamide, 3-(trifluoromethyl)-; 3-Trifluoromethylbenzamide; m-Trifluoromethylbenzamide; 3-Carbamoylbenzotrifluoride; 3-Aminocarbonylbenzotrifluoride
EINECS	217-300-4

Quality Control

Our 3-(Trifluoromethyl)Benzamide is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring high-purity intermediates for regulatory filings.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases. The product is moisture-sensitive; ensure containers are sealed after use to prevent absorption of water vapor.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	142 - 147 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.